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TRIM5α is a SUMO substrate

BACKGROUND: The TRIM5α restriction factor interferes with retroviral infections by inhibiting an early step of viral replication. TRIM5α activity was recently proposed to be regulated by the SUMO machinery and one SUMO consensus conjugation site as well as three putative SUMO interacting motifs (SIM...

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Detalles Bibliográficos
Autores principales:	Dutrieux, Jacques, Portilho, Débora M, Arhel, Nathalie J, Hazan, Uriel, Nisole, Sébastien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376147/ https://www.ncbi.nlm.nih.gov/pubmed/25880753 http://dx.doi.org/10.1186/s12977-015-0155-7

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