FRESCo: finding regions of excess synonymous constraint in diverse viruses

BACKGROUND: The increasing availability of sequence data for many viruses provides power to detect regions under unusual evolutionary constraint at a high resolution. One approach leverages the synonymous substitution rate as a signature to pinpoint genic regions encoding overlapping or embedded fun...

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Detalles Bibliográficos
Autores principales: Sealfon, Rachel S, Lin, Michael F, Jungreis, Irwin, Wolf, Maxim Y, Kellis, Manolis, Sabeti, Pardis C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376164/
https://www.ncbi.nlm.nih.gov/pubmed/25853568
http://dx.doi.org/10.1186/s13059-015-0603-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376164/
https://www.ncbi.nlm.nih.gov/pubmed/25853568
http://dx.doi.org/10.1186/s13059-015-0603-7

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