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FRESCo: finding regions of excess synonymous constraint in diverse viruses
BACKGROUND: The increasing availability of sequence data for many viruses provides power to detect regions under unusual evolutionary constraint at a high resolution. One approach leverages the synonymous substitution rate as a signature to pinpoint genic regions encoding overlapping or embedded fun...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376164/ https://www.ncbi.nlm.nih.gov/pubmed/25853568 http://dx.doi.org/10.1186/s13059-015-0603-7 |