A targeted analysis identifies a high frequency of BRCA1 and BRCA2 mutation carriers in women with ovarian cancer from a founder population

BACKGROUND: The frequency of BRCA1 and BRCA2 mutations in ovarian cancer patients varies depending on histological subtype and population investigated. The six most commonly recurring BRCA1 and BRCA2 mutations previously identified in a founder French Canadian population were investigated in 439 his...

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Detalles Bibliográficos
Autores principales: Belanger, Moria H, Dolman, Lena, Arcand, Suzanna L, Shen, Zhen, Chong, George, Mes-Masson, Anne-Marie, Provencher, Diane, Tonin, Patricia N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376165/
https://www.ncbi.nlm.nih.gov/pubmed/25884701
http://dx.doi.org/10.1186/s13048-015-0124-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376165/
https://www.ncbi.nlm.nih.gov/pubmed/25884701
http://dx.doi.org/10.1186/s13048-015-0124-8

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