Correlation between Activation of PI3K/AKT/mTOR Pathway and Prognosis of Breast Cancer in Chinese Women

BACKGROUND: Abnormal activation of PI3K/AKT/mTOR (PAM) pathway, caused by PIK3CA mutation, KRAS mutation, PTEN loss, or AKT1 mutation, is one of the most frequent signaling abnormalities in breast carcinoma. However, distribution and frequencies of mutations in PAM pathway are unclear in breast canc...

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Detalles Bibliográficos
Autores principales: Deng, Ling, Chen, Jie, Zhong, Xiao Rong, Luo, Ting, Wang, Yan Ping, Huang, Hui Fen, Yin, Li-Juan, Qiu, Yan, Bu, Hong, Lv, Qing, Zheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376391/
https://www.ncbi.nlm.nih.gov/pubmed/25816324
http://dx.doi.org/10.1371/journal.pone.0120511

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