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Rigosertib induces cell death of a myelodysplastic syndrome-derived cell line by DNA damage-induced G2/M arrest

A multi-kinase inhibitor, rigosertib (ON 01910.Na) has recently been highlighted as a novel type of anti-cancer agent for the treatment of the myelodysplastic syndromes (MDS), but its action mechanisms remain to be clarified. We investigated the in vitro effects of rigosertib on an MDS-derived cell...

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Detalles Bibliográficos
Autores principales:	Hyoda, Tomoko, Tsujioka, Takayuki, Nakahara, Takako, Suemori, Shin-ichiro, Okamoto, Shuichiro, Kataoka, Mikio, Tohyama, Kaoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376437/ https://www.ncbi.nlm.nih.gov/pubmed/25580850 http://dx.doi.org/10.1111/cas.12605

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