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Methamphetamine Self-Administration in Mice Decreases GIRK Channel-Mediated Currents in Midbrain Dopamine Neurons

BACKGROUND: Methamphetamine is a psychomotor stimulant with abuse liability and a substrate for catecholamine uptake transporters. Acute methamphetamine elevates extracellular dopamine, which in the midbrain can activate D2 autoreceptors to increase a G-protein gated inwardly rectifying potassium (G...

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Detalles Bibliográficos
Autores principales:	Sharpe, Amanda L., Varela, Erika, Bettinger, Lynne, Beckstead, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376542/ https://www.ncbi.nlm.nih.gov/pubmed/25522412 http://dx.doi.org/10.1093/ijnp/pyu073

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