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PI3K/AKT/mTOR Signaling-Mediated Neuropeptide VGF in the Hippocampus of Mice Is Involved in the Rapid Onset Antidepressant-Like Effects of GLYX-13
BACKGROUND: VGF (nonacryonimic) and phosphatidylinositol 3-kinase (PI3K)/AKT (also known as protein kinase B, PKB)/mammalian target of rapamycin (mTOR) signaling play pivotal roles in depression. However, whether phosphatidylinositol 3-kinase/AKT/mTOR signaling-mediated VGF participates in rapid-act...
Autores principales: | Lu, Yang, Wang, Chuang, Xue, Zhancheng, Li, Chenli, Zhang, Junfang, Zhao, Xin, Liu, Aiming, Wang, Qinwen, Zhou, Wenhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376553/ https://www.ncbi.nlm.nih.gov/pubmed/25542689 http://dx.doi.org/10.1093/ijnp/pyu110 |
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