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Lipidomic Analysis Links Mycobactin Synthase K to Iron Uptake and Virulence in M. tuberculosis

The prolonged survival of Mycobacterium tuberculosis (M. tb) in the host fundamentally depends on scavenging essential nutrients from host sources. M. tb scavenges non-heme iron using mycobactin and carboxymycobactin siderophores, synthesized by mycobactin synthases (Mbt). Although a general mechani...

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Detalles Bibliográficos
Autores principales:	Madigan, Cressida A., Martinot, Amanda Jezek, Wei, Jun-Rong, Madduri, Ashoka, Cheng, Tan-Yun, Young, David C., Layre, Emilie, Murry, Jeffrey P., Rubin, Eric J., Moody, D. Branch
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376628/ https://www.ncbi.nlm.nih.gov/pubmed/25815898 http://dx.doi.org/10.1371/journal.ppat.1004792

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