Cargando…
Gallic Acid Induces Necroptosis via TNF–α Signaling Pathway in Activated Hepatic Stellate Cells
Gallic acid (3, 4, 5-trihydroxybenzoic acid, GA), a natural phenolic acid widely found in gallnuts, tea leaves and various fruits, possesses several bioactivities against inflammation, oxidation, and carcinogenicity. The beneficial effect of GA on the reduction of animal hepatofibrosis has been indi...
Autores principales: | Chang, Ya Ju, Hsu, Shih Lan, Liu, Yi Ting, Lin, Yu Hsuan, Lin, Ming Hui, Huang, Shu Jung, Ho, Ja-an Annie, Wu, Li-Chen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376672/ https://www.ncbi.nlm.nih.gov/pubmed/25816210 http://dx.doi.org/10.1371/journal.pone.0120713 |
Ejemplares similares
-
Antifibrotic effects of gallic acid on hepatic stellate cells: In vitro and in vivo mechanistic study
por: El-Lakkany, Naglaa M., et al.
Publicado: (2018) -
Multiple functions of MLKL in liver fibrosis, from necroptosis to hepatic stellate cell activation
por: Pistorio, Valeria, et al.
Publicado: (2022) -
TNFα-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation
por: Huang, Wan-Yu, et al.
Publicado: (2022) -
Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation
por: Guo, Ren, et al.
Publicado: (2022) -
Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils
por: Wicki, Simone, et al.
Publicado: (2016)