Mutation in MRPS34 Compromises Protein Synthesis and Causes Mitochondrial Dysfunction

The evolutionary divergence of mitochondrial ribosomes from their bacterial and cytoplasmic ancestors has resulted in reduced RNA content and the acquisition of mitochondria-specific proteins. The mitochondrial ribosomal protein of the small subunit 34 (MRPS34) is a mitochondria-specific ribosomal p...

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Detalles Bibliográficos
Autores principales: Richman, Tara R., Ermer, Judith A., Davies, Stefan M. K., Perks, Kara L., Viola, Helena M., Shearwood, Anne-Marie J., Hool, Livia C., Rackham, Oliver, Filipovska, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376678/
https://www.ncbi.nlm.nih.gov/pubmed/25816300
http://dx.doi.org/10.1371/journal.pgen.1005089

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