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Actin-Mediated Gene Expression Depends on RhoA and Rac1 Signaling in Proximal Tubular Epithelial Cells

Morphological alterations of cells can lead to modulation of gene expression. An essential link is the MKL1-dependent activation of serum response factor (SRF), which translates changes in the ratio of G- and F-actin into mRNA transcription. SRF activation is only partially characterized in non-tran...

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Detalles Bibliográficos
Autores principales:	Giehl, Klaudia, Keller, Christof, Muehlich, Susanne, Goppelt-Struebe, Margarete
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376694/ https://www.ncbi.nlm.nih.gov/pubmed/25816094 http://dx.doi.org/10.1371/journal.pone.0121589

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