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Ccr4-Not Regulates RNA Polymerase I Transcription and Couples Nutrient Signaling to the Control of Ribosomal RNA Biogenesis

Ribosomal RNA synthesis is controlled by nutrient signaling through the mechanistic target of rapamycin complex 1 (mTORC1) pathway. mTORC1 regulates ribosomal RNA expression by affecting RNA Polymerase I (Pol I)-dependent transcription of the ribosomal DNA (rDNA) but the mechanisms involved remain o...

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Detalles Bibliográficos
Autores principales:	Laribee, R. Nicholas, Hosni-Ahmed, Amira, Workman, Jason J., Chen, Hongfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376722/ https://www.ncbi.nlm.nih.gov/pubmed/25815716 http://dx.doi.org/10.1371/journal.pgen.1005113

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