Cargando…

Lung Fibroblasts Share Mesenchymal Stem Cell Features Which Are Altered in Chronic Obstructive Pulmonary Disease via the Overactivation of the Hedgehog Signaling Pathway

BACKGROUND: Alteration of functional regenerative properties of parenchymal lung fibroblasts is widely proposed as a pathogenic mechanism for chronic obstructive pulmonary disease (COPD). However, what these functions are and how they are impaired in COPD remain poorly understood. Apart from the rol...

Descripción completa

Detalles Bibliográficos
Autores principales: Figeac, Florence, Dagouassat, Maylis, Mahrouf-Yorgov, Meriem, Le Gouvello, Sabine, Trébeau, Céline, Sayed, Angeliqua, Stern, Jean-Baptiste, Validire, Pierre, Dubois-Randé, Jean-Luc, Boczkowski, Jorge, Mus-Veteau, Isabelle, Rodriguez, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376723/
https://www.ncbi.nlm.nih.gov/pubmed/25815884
http://dx.doi.org/10.1371/journal.pone.0121579