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C-C Chemokine Receptor 2 Inhibitor Ameliorates Hepatic Steatosis by Improving ER Stress and Inflammation in a Type 2 Diabetic Mouse Model
Hepatic steatosis is the accumulation of excess fat in the liver. Recently, hepatic steatosis has become more important because it occurs in the patients with obesity, type 2 diabetes, and hyperlipidemia and is associated with endoplasmic reticulum (ER) stress and insulin resistance. C-C chemokine r...
Autores principales: | Kim, Hong-Min, Lee, Eun Soo, Lee, Bo Ra, Yadav, Dhananjay, Kim, You Mi, Ko, Hyun-Jeong, Park, Kyu Sang, Lee, Eun Young, Chung, Choon Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376739/ https://www.ncbi.nlm.nih.gov/pubmed/25816097 http://dx.doi.org/10.1371/journal.pone.0120711 |
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