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Pharmacokinetics and Tolerability of Inhaled Umeclidinium and Vilanterol Alone and in Combination in Healthy Chinese Subjects: A Randomized, Open-Label, Crossover Trial

Inhaled umeclidinium (UMEC) and the combination of inhaled UMEC with vilanterol (UMEC/VI) are approved maintenance treatments for chronic obstructive pulmonary disease in the US and EU. This was a randomized, open-label, three-period crossover, single- and repeat-dose study to assess the pharmacokin...

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Detalles Bibliográficos
Autores principales: Hu, Chaoying, Jia, Jingying, Dong, Kelly, Luo, Linda, Wu, Kai, Mehta, Rashmi, Peng, Jack, Ren, Yan, Gross, Annette, Yu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376748/
https://www.ncbi.nlm.nih.gov/pubmed/25816315
http://dx.doi.org/10.1371/journal.pone.0121264