Cargando…

Improvement in Plasma Drug Activity during the Early Treatment Interval among Tanzanian Patients with Multidrug-Resistant Tuberculosis

BACKGROUND: Individual pharmacokinetic variability may be common in patients treated for multidrug-resistant tuberculosis (MDR-TB) but data are sparse from resource-limited settings and across the early treatment interval. METHODS: Plasma drug activity, as measured by the TB Drug Activity (TDA) assa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ndusilo, Norah D., Heysell, Scott K., Mpagama, Stellah G., Gratz, Jean, Segesela, Farida H., Pazia, Saumu J., Wang, Xin-Qun, Houpt, Eric R., Kibiki, Gibson S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376785/ https://www.ncbi.nlm.nih.gov/pubmed/25816161 http://dx.doi.org/10.1371/journal.pone.0122769

Ejemplares similares

Underestimated pyrazinamide resistance may compromise outcomes of pyrazinamide containing regimens for treatment of drug susceptible and multi-drug-resistant tuberculosis in Tanzania
por: Juma, Saumu Pazia, et al.
Publicado: (2019)

Application of quantitative second-line drug susceptibility testing at a multidrug-resistant tuberculosis hospital in Tanzania
por: Mpagama, Stellah G, et al.
Publicado: (2013)

Diagnosis and Interim Treatment Outcomes from the First Cohort of Multidrug-Resistant Tuberculosis Patients in Tanzania
por: Mpagama, Stellah G., et al.
Publicado: (2013)

Evaluation of the Antibody in Lymphocyte Supernatant Assay to Detect Active Tuberculosis
por: Sariko, Margaretha, et al.
Publicado: (2017)

Gridlock from diagnosis to treatment of multidrug resistant tuberculosis (MDR-TB) in Tanzania: patients’ perspectives from a focus group discussion
por: Mpagama, Stellah G., et al.
Publicado: (2020)

Comparison of Overnight Pooled and Standard Sputum Collection Method for Patients with Suspected Pulmonary Tuberculosis in Northern Tanzania
por: Mpagama, Stellah G., et al.
Publicado: (2012)

Evaluation of cytokines in peripheral blood mononuclear cell supernatants for the diagnosis of tuberculosis
por: Sariko, Margaretha, et al.
Publicado: (2018)

Prevalence and extent of heteroresistance by next generation sequencing of multidrug-resistant tuberculosis
por: Operario, Darwin J., et al.
Publicado: (2017)

Gridlock from diagnosis to treatment of multidrug-resistant tuberculosis in Tanzania: low accessibility of molecular diagnostic services and lack of healthcare worker empowerment in 28 districts of 5 high burden TB regions with mixed methods evaluation
por: Mpagama, Stellah G., et al.
Publicado: (2019)

Determination of plasma concentrations of levofloxacin by high performance liquid chromatography for use at a multidrug-resistant tuberculosis hospital in Tanzania
por: Ebers, Andrew, et al.
Publicado: (2017)

Correction: Prevalence and extent of heteroresistance by next generation sequencing of multidrug-resistant tuberculosis
por: Operario, Darwin J., et al.
Publicado: (2017)

Pharmacodynamic Biomarkers for Quantifying the Mycobacterial Effect of High Doses of Rifampin in Patients with Rifampin-susceptible Pulmonary Tuberculosis
por: Said, Bibie N, et al.
Publicado: (2021)

Gridlock from Diagnosis to Treatment of Multidrug-Resistant Tuberculosis (MDR-TB) in Tanzania: Illuminating Potential Factors for Possible Intervention
por: Liyoyo, Alphonce A, et al.
Publicado: (2017)

Diagnostic Opportunities for Optimizing Management of Multidrug-Resistant Tuberculosis (MDR-TB) in Tanzania
por: Mpagama, Stellah G
Publicado: (2018)

Protocol for a feasibility randomized controlled trial to evaluate the efficacy, safety and tolerability of N-acetylcysteine in reducing adverse drug reactions among adults treated for multidrug-resistant tuberculosis in Tanzania
por: Mpagama, Stellah G., et al.
Publicado: (2023)

Whole genome sequencing-based drug resistance predictions of multidrug-resistant Mycobacterium tuberculosis isolates from Tanzania
por: Mbelele, Peter M., et al.
Publicado: (2022)

TB or not TB? Definitive determination of species within the M ycobacterium tuberculosis complex in unprocessed sputum from adults with presumed multidrug‐resistant tuberculosis
por: Mbelele, Peter M., et al.
Publicado: (2021)

Meta-Narrative Review of Molecular Methods for Diagnosis and Monitoring of Multidrug-Resistant Tuberculosis Treatment in Adults
por: Mbelele, Peter M., et al.
Publicado: (2018)

Population Pharmacokinetics of Levofloxacin and Moxifloxacin, and the Probability of Target Attainment in Ethiopian Patients with Multidrug-Resistant Tuberculosis
por: Sidamo, Temesgen, et al.
Publicado: (2022)

Drug-Susceptible and Multidrug-Resistant Mycobacterium tuberculosis in a Single Patient
por: Baffoe-Bonnie, Anthony, et al.
Publicado: (2019)

Enteropathogen spectrum and effect on antimycobacterial pharmacokinetics among children with tuberculosis in rural Tanzania: a prospective cohort study
por: Van Aartsen, Daniel, et al.
Publicado: (2022)

Integrated Microfluidic Card with TaqMan Probes and High-Resolution Melt Analysis To Detect Tuberculosis Drug Resistance Mutations across 10 Genes
por: Pholwat, Suporn, et al.
Publicado: (2015)

Quantitative Drug-Susceptibility in Patients Treated for Multidrug-Resistant Tuberculosis in Bangladesh: Implications for Regimen Choice
por: Heysell, Scott K., et al.
Publicado: (2015)

Outcomes and Use of Therapeutic Drug Monitoring in Multidrug-Resistant Tuberculosis Patients Treated in Virginia, 2009-2014
por: Heysell, Scott K., et al.
Publicado: (2015)

Multiple Pathogens Contribute to Human Immunodeficiency Virus-Related Sepsis in Addition to Mycobacterium tuberculosis: A Prospective Cohort in Tanzania
por: Tsere, Donatus Bonphace, et al.
Publicado: (2022)

Mycobactericidal Effects of Different Regimens Measured by Molecular Bacterial Load Assay among People Treated for Multidrug-Resistant Tuberculosis in Tanzania
por: Mbelele, Peter M., et al.
Publicado: (2021)

Decision Analytic Modeling for Global Clinical Trial Planning: A Case for HIV-Positive Patients at High Risk for Mycobacterium tuberculosis Sepsis in Uganda
por: Keim-Malpass, Jessica, et al.
Publicado: (2023)

Primary Multidrug-Resistant Mycobacterium tuberculosis in 2 Regions, Eastern Siberia, Russian Federation
por: Zhdanova, Svetlana, et al.
Publicado: (2013)

Pharmacokinetic-Pharmacodynamic Determinants of Clinical Outcomes for Rifampin-Resistant Tuberculosis: A Multisite Prospective Cohort Study
por: Heysell, Scott K, et al.
Publicado: (2022)

Whole-genome sequencing of SARS-CoV-2 isolates from symptomatic and asymptomatic individuals in Tanzania
por: Mziray, Shabani Ramadhani, et al.
Publicado: (2023)

Pyrazinamide Susceptibility and pncA Mutation Profiles of Mycobacterium tuberculosis among Multidrug-Resistant Tuberculosis Patients in Bangladesh
por: Rahman, Arfatur, et al.
Publicado: (2017)

Protocol for establishing an Adaptive Diseases control Expert Programme in Tanzania (ADEPT) for integrating care of communicable and non-communicable diseases using tuberculosis and diabetes as a case study
por: Mpagama, Stellah G, et al.
Publicado: (2021)

Coinfection of COVID-19 and Tuberculosis in Uganda
por: Nuwagira, Edwin, et al.
Publicado: (2023)

Whole genome sequencing of Mycobacterium tuberculosis isolates and clinical outcomes of patients treated for multidrug-resistant tuberculosis in Tanzania
por: Katale, Bugwesa Z., et al.
Publicado: (2020)

A mobile microvolume UV/visible light spectrophotometer for the measurement of levofloxacin in saliva
por: Alffenaar, Jan-Willem C, et al.
Publicado: (2020)

Effect of diabetes mellitus on TB drug concentrations in Tanzanian patients
por: Mtabho, Charles M, et al.
Publicado: (2019)

Early interventions for diabetes related tuberculosis associate with hastened sputum microbiological clearance in Virginia, USA
por: Alkabab, Yosra, et al.
Publicado: (2017)

Therapeutic Drug Monitoring for Slow Response to Tuberculosis Treatment in a State Control Program, Virginia, USA
por: Heysell, Scott K., et al.
Publicado: (2010)

Improved performance of Xpert MTB/RIF assay on sputum sediment samples obtained from presumptive pulmonary tuberculosis cases at Kibong’oto infectious diseases hospital in Tanzania
por: Mbelele, Peter M., et al.
Publicado: (2017)

Clinical-demographic markers for improving diabetes mellitus diagnosis in people with tuberculosis in Tanzania
por: Byashalira, Kenneth Cleophace, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6ph1g17r413b00th6jacbfgu22