Cargando…

MiR-145 Inhibits Metastasis by Targeting Fascin Actin-Bundling Protein 1 in Nasopharyngeal Carcinoma

BACKGROUND: Based on our recent microarray analysis, we found that miR-145 was obviously downregulated in nasopharyngeal carcinoma (NPC) tissues. However, little is known about its function and mechanism involving in NPC development and progression. METHODS: Quantitative RT-PCR was used to detect mi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ying-Qin, He, Qing-Mei, Ren, Xian-Yue, Tang, Xin-Ran, Xu, Ya-Fei, Wen, Xin, Yang, Xiao-Jing, Ma, Jun, Liu, Na
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376852/ https://www.ncbi.nlm.nih.gov/pubmed/25816323 http://dx.doi.org/10.1371/journal.pone.0122228

Ejemplares similares

Strong fascin expression promotes metastasis independent of its F-actin bundling activity
por: Heinz, Lisa S., et al.
Publicado: (2017)

Fascin in Cell Migration: More Than an Actin Bundling Protein
por: Lamb, Maureen C., et al.
Publicado: (2020)

The actin-bundling protein Fascin-1 modulates ciliary signalling
por: Brücker, Lena, et al.
Publicado: (2023)

Fascin promotes filopodia formation independent of its role in actin bundling
por: Zanet, Jennifer, et al.
Publicado: (2012)

IKKε inhibits PKC to promote Fascin-dependent actin bundling
por: Otani, Tetsuhisa, et al.
Publicado: (2016)

The Actin Bundling Protein Fascin-1 as an ACE2-Accessory Protein
por: Ogunlade, Blessing, et al.
Publicado: (2020)

beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex
Publicado: (1996)

Structural Analysis of Human Fascin-1: Essential Protein for Actin Filaments Bundling
por: Chung, Jeong Min, et al.
Publicado: (2022)

Cooperative bundling by fascin generates actin structures with architectures that depend on filament length
por: Sherer, Laura A., et al.
Publicado: (2022)

The Cluster of miR-143 and miR-145 Affects the Risk for Esophageal Squamous Cell Carcinoma through Co-Regulating Fascin Homolog 1
por: Liu, Ran, et al.
Publicado: (2012)

Fascin actin-bundling protein 1 in human cancer: promising biomarker or therapeutic target?
por: Liu, Hongliang, et al.
Publicado: (2021)

The actin bundling protein Fascin is important for proper early development in Strongylocentrotus purpuratus embryos
por: Testa, Michael D., et al.
Publicado: (2023)

Fascin, an actin-bundling protein associated with cell motility, is upregulated in hormone receptor negative breastancer
por: Grothey, A, et al.
Publicado: (2000)

The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro
por: Qualtrough, D, et al.
Publicado: (2009)

The actin-bundling protein Fascin is overexpressed in inflammatory bowel disease and may be important in tissue repair
por: Qualtrough, David, et al.
Publicado: (2011)

The Chlamydia trachomatis Early Effector Tarp Outcompetes Fascin in Forming F-Actin Bundles In Vivo
por: Aranjuez, George F., et al.
Publicado: (2022)

MicroRNA-145 inhibits tumour growth and metastasis in colorectal cancer by targeting fascin-1
por: Feng, Y, et al.
Publicado: (2014)

Drosophila singed, a fascin homolog, is required for actin bundle formation during oogenesis and bristle extension
Publicado: (1994)

Ena/VASP processive elongation is modulated by avidity on actin filaments bundled by the filopodia cross-linker fascin
por: Harker, Alyssa J., et al.
Publicado: (2019)

Confinement Geometry Tunes Fascin-Actin Bundle Structures and Consequently the Shape of a Lipid Bilayer Vesicle
por: Bashirzadeh, Yashar, et al.
Publicado: (2020)

Fascin lysine 471 acetylation cooperates with serine 39 phosphorylation to inhibit actin‐bundling activity and tumor metastasis in esophageal squamous cell carcinoma
por: Zeng, Fa‐Min, et al.
Publicado: (2022)

miR-143 and miR-145 inhibit gastric cancer cell migration and metastasis by suppressing MYO6
por: Lei, Chao, et al.
Publicado: (2017)

Inhibitors of the Actin-Bundling Protein Fascin-1 Developed for Tumor Therapy Attenuate the T-Cell Stimulatory Properties of Dendritic Cells
por: Zeyn, Yanira, et al.
Publicado: (2022)

P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer
por: Cheng, Yin‐Wei, et al.
Publicado: (2021)

Fascin regulates nuclear actin during Drosophila oogenesis
por: Kelpsch, Daniel J., et al.
Publicado: (2016)

Migrastatin Analogues Target Fascin to Block Tumor Metastasis
por: Chen, Lin, et al.
Publicado: (2010)

The targeting of MTDH by miR-145-5p or miR-145-3p is associated with prognosis and regulates the growth and metastasis of prostate cancer cells
por: Pan, Dong, et al.
Publicado: (2019)

The targeting of MTDH by miR-145-5p or miR-145-3p is associated with prognosis and regulates the growth and metastasis of prostate cancer cells
por: Pan, Dong, et al.
Publicado: (2023)

Epigenetic silencing of miR-145-5p contributes to brain metastasis
por: Donzelli, Sara, et al.
Publicado: (2015)

Epigenetically regulated miR-145 suppresses colon cancer invasion and metastasis by targeting LASP1
por: Wang, Wei, et al.
Publicado: (2016)

YPEL3 suppresses epithelial–mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway
por: Zhang, Jian, et al.
Publicado: (2016)

MicroRNA-101 inhibits invasion and angiogenesis through targeting ITGA3 and its systemic delivery inhibits lung metastasis in nasopharyngeal carcinoma
por: Tang, Xin-Ran, et al.
Publicado: (2017)

Berberine inhibited metastasis through miR-145/MMP16 axis in vitro
por: Li, Jie, et al.
Publicado: (2021)

Correction to: YPEL3 suppresses epithelial–mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway
por: Zhang, Jian, et al.
Publicado: (2020)

Correction to: YPEL3 suppresses epithelial–mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway
por: Zhang, Jian, et al.
Publicado: (2021)

Anti-Metastasis Fascin Inhibitors Decrease the Growth of Specific Subtypes of Cancers
por: Wang, Yufeng, et al.
Publicado: (2020)

Regulation of intraocular pressure by microRNA cluster miR-143/145
por: Li, Xinyu, et al.
Publicado: (2017)

Roles of Fascin in Dendritic Cells
por: Wang, Hao-Jie, et al.
Publicado: (2023)

The Tax-Inducible Actin-Bundling Protein Fascin Is Crucial for Release and Cell-to-Cell Transmission of Human T-Cell Leukemia Virus Type 1 (HTLV-1)
por: Gross, Christine, et al.
Publicado: (2016)

MicroRNA-133a inhibits proliferation and invasion, and induces apoptosis in gastric carcinoma cells via targeting fascin actin-bundling protein 1
por: Lai, Chen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8uk0532fd3mb7cm00p7vgrrn94