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Heritable CRISPR/Cas9-Mediated Genome Editing in the Yellow Fever Mosquito, Aedes aegypti

In vivo targeted gene disruption is a powerful tool to study gene function. Thus far, two tools for genome editing in Aedes aegypti have been applied, zinc-finger nucleases (ZFN) and transcription activator-like effector nucleases (TALEN). As a promising alternative to ZFN and TALEN, which are diffi...

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Detalles Bibliográficos
Autores principales:	Dong, Shengzhang, Lin, Jingyi, Held, Nicole L., Clem, Rollie J., Passarelli, A. Lorena, Franz, Alexander W. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376861/ https://www.ncbi.nlm.nih.gov/pubmed/25815482 http://dx.doi.org/10.1371/journal.pone.0122353

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