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A Novel Three-Filament Model of Force Generation in Eccentric Contraction of Skeletal Muscles
We propose and examine a three filament model of skeletal muscle force generation, thereby extending classical cross-bridge models by involving titin-actin interaction upon active force production. In regions with optimal actin-myosin overlap, the model does not alter energy and force predictions of...
Autores principales: | Schappacher-Tilp, Gudrun, Leonard, Timothy, Desch, Gertrud, Herzog, Walter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376863/ https://www.ncbi.nlm.nih.gov/pubmed/25816319 http://dx.doi.org/10.1371/journal.pone.0117634 |
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