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Development and Validation of a 3-Plex RT-qPCR Assay for the Simultaneous Detection and Quantitation of the Three PML-RARa Fusion Transcripts in Acute Promyelocytic Leukemia

Rapid diagnosis of acute promyelocytic leukemia (APL) with promyelocytic leukemia-retinoic acid receptor alpha (PML-RARa) contributes to a highly effective therapy with all-trans retinoic acid (ATRA). Real-time quantitative reverse transcription-polymerase chain reaction (RT-qPCR) is a valuable tool...

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Detalles Bibliográficos
Autores principales:	Chen, Zhanguo, Tong, Yongqing, Li, Yan, Gao, Qingping, Wang, Qiongyu, Fu, Chaohong, Xia, Zunen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376893/ https://www.ncbi.nlm.nih.gov/pubmed/25815789 http://dx.doi.org/10.1371/journal.pone.0122530

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