Cargando…
Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature
Synovial cell sarcoma (SCS) of the kidney is a rare tumor entity with a poor prognosis. Morphologic and immunohistochemical characteristics may overlap with other more common neoplasms of the kidney. Therefore, the diagnosis of primary renal SCS not only requires the exclusion of similar tumor types...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376929/ https://www.ncbi.nlm.nih.gov/pubmed/25873878 http://dx.doi.org/10.1159/000379740 |
_version_ | 1782363814495256576 |
---|---|
author | Vedana, Marc Fuenfschilling, Maya Tzankov, Alexandar Zellweger, Tobias |
author_facet | Vedana, Marc Fuenfschilling, Maya Tzankov, Alexandar Zellweger, Tobias |
author_sort | Vedana, Marc |
collection | PubMed |
description | Synovial cell sarcoma (SCS) of the kidney is a rare tumor entity with a poor prognosis. Morphologic and immunohistochemical characteristics may overlap with other more common neoplasms of the kidney. Therefore, the diagnosis of primary renal SCS not only requires the exclusion of similar tumor types, but also a confirmation of SYT-SSX gene fusion using molecular techniques. The treatment comprises radical surgery, and, depending on age and health status, adjuvant chemotherapy in selected patients. Here, we present an elderly SCS patient in whom straightforward radical surgical treatment resulted in a sustained complete remission; it allowed us to perform a literature survey focusing on current diagnostic tools for SCS. |
format | Online Article Text |
id | pubmed-4376929 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-43769292015-04-14 Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature Vedana, Marc Fuenfschilling, Maya Tzankov, Alexandar Zellweger, Tobias Case Rep Oncol Published online: March, 2015 Synovial cell sarcoma (SCS) of the kidney is a rare tumor entity with a poor prognosis. Morphologic and immunohistochemical characteristics may overlap with other more common neoplasms of the kidney. Therefore, the diagnosis of primary renal SCS not only requires the exclusion of similar tumor types, but also a confirmation of SYT-SSX gene fusion using molecular techniques. The treatment comprises radical surgery, and, depending on age and health status, adjuvant chemotherapy in selected patients. Here, we present an elderly SCS patient in whom straightforward radical surgical treatment resulted in a sustained complete remission; it allowed us to perform a literature survey focusing on current diagnostic tools for SCS. S. Karger AG 2015-03-03 /pmc/articles/PMC4376929/ /pubmed/25873878 http://dx.doi.org/10.1159/000379740 Text en Copyright © 2015 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published online: March, 2015 Vedana, Marc Fuenfschilling, Maya Tzankov, Alexandar Zellweger, Tobias Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature |
title | Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature |
title_full | Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature |
title_fullStr | Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature |
title_full_unstemmed | Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature |
title_short | Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature |
title_sort | primary synovial cell sarcoma of the kidney: case report and review of the literature |
topic | Published online: March, 2015 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376929/ https://www.ncbi.nlm.nih.gov/pubmed/25873878 http://dx.doi.org/10.1159/000379740 |
work_keys_str_mv | AT vedanamarc primarysynovialcellsarcomaofthekidneycasereportandreviewoftheliterature AT fuenfschillingmaya primarysynovialcellsarcomaofthekidneycasereportandreviewoftheliterature AT tzankovalexandar primarysynovialcellsarcomaofthekidneycasereportandreviewoftheliterature AT zellwegertobias primarysynovialcellsarcomaofthekidneycasereportandreviewoftheliterature |