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BACA: bubble chArt to compare annotations
BACKGROUND: DAVID is the most popular tool for interpreting large lists of gene/proteins classically produced in high-throughput experiments. However, the use of DAVID website becomes difficult when analyzing multiple gene lists, for it does not provide an adequate visualization tool to show/compare...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377007/ https://www.ncbi.nlm.nih.gov/pubmed/25652236 http://dx.doi.org/10.1186/s12859-015-0477-4 |
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author | Fortino, Vittorio Alenius, Harri Greco, Dario |
author_facet | Fortino, Vittorio Alenius, Harri Greco, Dario |
author_sort | Fortino, Vittorio |
collection | PubMed |
description | BACKGROUND: DAVID is the most popular tool for interpreting large lists of gene/proteins classically produced in high-throughput experiments. However, the use of DAVID website becomes difficult when analyzing multiple gene lists, for it does not provide an adequate visualization tool to show/compare multiple enrichment results in a concise and informative manner. RESULT: We implemented a new R-based graphical tool, BACA (Bubble chArt to Compare Annotations), which uses the DAVID web service for cross-comparing enrichment analysis results derived from multiple large gene lists. BACA is implemented in R and is freely available at the CRAN repository (http://cran.r-project.org/web/packages/BACA/). CONCLUSION: The package BACA allows R users to combine multiple annotation charts into one output graph by passing DAVID website. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12859-015-0477-4) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4377007 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-43770072015-03-29 BACA: bubble chArt to compare annotations Fortino, Vittorio Alenius, Harri Greco, Dario BMC Bioinformatics Software BACKGROUND: DAVID is the most popular tool for interpreting large lists of gene/proteins classically produced in high-throughput experiments. However, the use of DAVID website becomes difficult when analyzing multiple gene lists, for it does not provide an adequate visualization tool to show/compare multiple enrichment results in a concise and informative manner. RESULT: We implemented a new R-based graphical tool, BACA (Bubble chArt to Compare Annotations), which uses the DAVID web service for cross-comparing enrichment analysis results derived from multiple large gene lists. BACA is implemented in R and is freely available at the CRAN repository (http://cran.r-project.org/web/packages/BACA/). CONCLUSION: The package BACA allows R users to combine multiple annotation charts into one output graph by passing DAVID website. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12859-015-0477-4) contains supplementary material, which is available to authorized users. BioMed Central 2015-02-05 /pmc/articles/PMC4377007/ /pubmed/25652236 http://dx.doi.org/10.1186/s12859-015-0477-4 Text en © Fortino et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Software Fortino, Vittorio Alenius, Harri Greco, Dario BACA: bubble chArt to compare annotations |
title | BACA: bubble chArt to compare annotations |
title_full | BACA: bubble chArt to compare annotations |
title_fullStr | BACA: bubble chArt to compare annotations |
title_full_unstemmed | BACA: bubble chArt to compare annotations |
title_short | BACA: bubble chArt to compare annotations |
title_sort | baca: bubble chart to compare annotations |
topic | Software |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377007/ https://www.ncbi.nlm.nih.gov/pubmed/25652236 http://dx.doi.org/10.1186/s12859-015-0477-4 |
work_keys_str_mv | AT fortinovittorio bacabubblecharttocompareannotations AT aleniusharri bacabubblecharttocompareannotations AT grecodario bacabubblecharttocompareannotations |