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The effectiveness of Tai Chi for patients with Parkinson’s disease: study protocol for a randomized controlled trial
BACKGROUND: Parkinson’s disease (PD) is a common degenerative neurological disorder that causes loss of independence and decreased quality of life. The prevalence of PD tends to increase with age. In China, the morbidity rate of PD among people aged more than 65 years old is 1.70%. As an important c...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377011/ https://www.ncbi.nlm.nih.gov/pubmed/25873334 http://dx.doi.org/10.1186/s13063-015-0639-8 |
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author | Yang, Yan Hao, Yan-lei Tian, Wen-jing Gong, Li Zhang, Kui Shi, Qi-guang Sun, Da-fang Li, Cui-lan Zhao, Zhi-ling |
author_facet | Yang, Yan Hao, Yan-lei Tian, Wen-jing Gong, Li Zhang, Kui Shi, Qi-guang Sun, Da-fang Li, Cui-lan Zhao, Zhi-ling |
author_sort | Yang, Yan |
collection | PubMed |
description | BACKGROUND: Parkinson’s disease (PD) is a common degenerative neurological disorder that causes loss of independence and decreased quality of life. The prevalence of PD tends to increase with age. In China, the morbidity rate of PD among people aged more than 65 years old is 1.70%. As an important component of traditional Chinese Qigong exercises, Tai Chi is a popular and safe exercise, especially for older adults in China. And it may result in promising gains for PD patients. However, current evidence is insufficient to inform the use of Tai Chi in the management of PD. Therefore, the aim of this trial is to systematically evaluate the effect of Tai Chi on PD and determine whether Tai Chi is an eligible exercise program for Chinese PD patients. METHODS/DESIGN: A single-blind, parallel randomized controlled trial will be conducted. One hundred and forty-two patients with PD will be randomly assigned to a Tai Chi group (n = 71) or routine exercise group (n = 71). Subjects will participate in supervised study programs 3 times per week for 2 months and will be followed for an additional 6 months after formal training stops. The primary outcome measures include Berg Balance Scale, Timed Up and Go Test and Six-Minute Walk Test, which are known to be valid and reliable clinical instruments. The Unified Parkinson’s Disease Rating Scale Motor Section and Parkinson’s Disease Questionnaire-39 will be used as the secondary outcome measure. All outcomes will be measured at baseline, 2 and 8 months. The sample for this trial (N = 142) will provide relevant information to detect the improvement of balance, gait and quality of life in either of the 2 exercise groups. DISCUSSION: Findings from this study will provide insights into the effects of Tai Chi in people with PD. The information gained from this project has the potential to influence the clinical decisions of Chinese doctors, and will provide clear evidence as to whether Tai Chi should be advocated in people with PD. TRIAL REGISTRATION: The trial was registered at (ChiCTR-TRC-14004549) on 22 April 2014. |
format | Online Article Text |
id | pubmed-4377011 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-43770112015-03-29 The effectiveness of Tai Chi for patients with Parkinson’s disease: study protocol for a randomized controlled trial Yang, Yan Hao, Yan-lei Tian, Wen-jing Gong, Li Zhang, Kui Shi, Qi-guang Sun, Da-fang Li, Cui-lan Zhao, Zhi-ling Trials Study Protocol BACKGROUND: Parkinson’s disease (PD) is a common degenerative neurological disorder that causes loss of independence and decreased quality of life. The prevalence of PD tends to increase with age. In China, the morbidity rate of PD among people aged more than 65 years old is 1.70%. As an important component of traditional Chinese Qigong exercises, Tai Chi is a popular and safe exercise, especially for older adults in China. And it may result in promising gains for PD patients. However, current evidence is insufficient to inform the use of Tai Chi in the management of PD. Therefore, the aim of this trial is to systematically evaluate the effect of Tai Chi on PD and determine whether Tai Chi is an eligible exercise program for Chinese PD patients. METHODS/DESIGN: A single-blind, parallel randomized controlled trial will be conducted. One hundred and forty-two patients with PD will be randomly assigned to a Tai Chi group (n = 71) or routine exercise group (n = 71). Subjects will participate in supervised study programs 3 times per week for 2 months and will be followed for an additional 6 months after formal training stops. The primary outcome measures include Berg Balance Scale, Timed Up and Go Test and Six-Minute Walk Test, which are known to be valid and reliable clinical instruments. The Unified Parkinson’s Disease Rating Scale Motor Section and Parkinson’s Disease Questionnaire-39 will be used as the secondary outcome measure. All outcomes will be measured at baseline, 2 and 8 months. The sample for this trial (N = 142) will provide relevant information to detect the improvement of balance, gait and quality of life in either of the 2 exercise groups. DISCUSSION: Findings from this study will provide insights into the effects of Tai Chi in people with PD. The information gained from this project has the potential to influence the clinical decisions of Chinese doctors, and will provide clear evidence as to whether Tai Chi should be advocated in people with PD. TRIAL REGISTRATION: The trial was registered at (ChiCTR-TRC-14004549) on 22 April 2014. BioMed Central 2015-03-24 /pmc/articles/PMC4377011/ /pubmed/25873334 http://dx.doi.org/10.1186/s13063-015-0639-8 Text en © Yang et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Study Protocol Yang, Yan Hao, Yan-lei Tian, Wen-jing Gong, Li Zhang, Kui Shi, Qi-guang Sun, Da-fang Li, Cui-lan Zhao, Zhi-ling The effectiveness of Tai Chi for patients with Parkinson’s disease: study protocol for a randomized controlled trial |
title | The effectiveness of Tai Chi for patients with Parkinson’s disease: study protocol for a randomized controlled trial |
title_full | The effectiveness of Tai Chi for patients with Parkinson’s disease: study protocol for a randomized controlled trial |
title_fullStr | The effectiveness of Tai Chi for patients with Parkinson’s disease: study protocol for a randomized controlled trial |
title_full_unstemmed | The effectiveness of Tai Chi for patients with Parkinson’s disease: study protocol for a randomized controlled trial |
title_short | The effectiveness of Tai Chi for patients with Parkinson’s disease: study protocol for a randomized controlled trial |
title_sort | effectiveness of tai chi for patients with parkinson’s disease: study protocol for a randomized controlled trial |
topic | Study Protocol |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377011/ https://www.ncbi.nlm.nih.gov/pubmed/25873334 http://dx.doi.org/10.1186/s13063-015-0639-8 |
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