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Presence of circulating Her2-reactive CD8 + T-cells is associated with lower frequencies of myeloid-derived suppressor cells and regulatory T cells, and better survival in older breast cancer patients

INTRODUCTION: Breast cancer is one of the most common cancers among women. Its incidence is increasing in many countries and a higher number of older women are now being diagnosed with the disease. Immune parameters are implicated in disease progression, and the frequencies of both myeloid-derived s...

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Detalles Bibliográficos
Autores principales: Bailur, Jithendra Kini, Gueckel, Brigitte, Derhovanessian, Evelyna, Pawelec, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377034/
https://www.ncbi.nlm.nih.gov/pubmed/25849846
http://dx.doi.org/10.1186/s13058-015-0541-z