Cargando…

Mesenchymal Stromal Cells: Inhibiting PDGF Receptors or Depleting Fibronectin Induces Mesodermal Progenitors with Endothelial Potential

Realizing the full therapeutic potential of mesenchymal stromal/stem cells (MSCs) awaits improved understanding of mechanisms controlling their fate. Using MSCs cultured as spheroids to recapitulate a three-dimensional cellular environment, we show that perturbing the mesenchymal regulators, platele...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ball, S G, Worthington, J J, Canfield, A E, Merry, C L R, Kielty, C M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Tissue-Specific Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377076/ https://www.ncbi.nlm.nih.gov/pubmed/24022915 http://dx.doi.org/10.1002/stem.1538

Ejemplares similares

Canonical Wnt Signaling Promotes Neovascularization Through Determination of Endothelial Progenitor Cell Fate via Metabolic Profile Regulation
por: Shao, Yan, et al.
Publicado: (2019)

Mesenchymal Stromal Cell Secretion of Programmed Death‐1 Ligands Regulates T Cell Mediated Immunosuppression
por: Davies, Lindsay C., et al.
Publicado: (2016)

FZD5 regulates cellular senescence in human mesenchymal stem/stromal cells
por: Harada, Seiko, et al.
Publicado: (2020)

Optimizing beta cell function through mesenchymal stromal cell‐mediated mitochondria transfer
por: Rackham, Chloe L., et al.
Publicado: (2020)

Mesenchymal Stromal Cells Express GARP/LRRC32 on Their Surface: Effects on Their Biology and Immunomodulatory Capacity
por: Carrillo-Galvez, Ana Belén, et al.
Publicado: (2015)

Concise Review: Modulating Cancer Immunity with Hematopoietic Stem and Progenitor Cells
por: Wildes, Tyler J., et al.
Publicado: (2018)

mDia1 and Cdc42 Regulate Activin B‐Induced Migration of Bone Marrow‐Derived Mesenchymal Stromal Cells
por: Wang, Xueer, et al.
Publicado: (2018)

CHD7 Maintains Neural Stem Cell Quiescence and Prevents Premature Stem Cell Depletion in the Adult Hippocampus
por: Jones, Kieran M., et al.
Publicado: (2014)

Prospective Identification and Isolation of Enteric Nervous System Progenitors Using Sox2
por: Heanue, Tiffany A, et al.
Publicado: (2011)

Concise Review: Kidney Stem/Progenitor Cells: Differentiate, Sort Out, or Reprogram?
por: Pleniceanu, Oren, et al.
Publicado: (2010)

Concise Review: Evidence for CD34 as a Common Marker for Diverse Progenitors
por: Sidney, Laura E, et al.
Publicado: (2014)

Telomerase expression marks transitional growth‐associated skeletal progenitor/stem cells
por: Carlone, Diana L., et al.
Publicado: (2021)

IP6K1 Reduces Mesenchymal Stem/Stromal Cell Fitness and Potentiates High Fat Diet‐Induced Skeletal Involution
por: Boregowda, Siddaraju V., et al.
Publicado: (2017)

Immunomodulatory Functions of Adipose Mesenchymal Stromal/Stem Cell Derived From Donors With Type 2 Diabetes and Obesity on CD4 T Cells
por: Mahmoud, Marwa, et al.
Publicado: (2023)

P2X7 Receptors Regulate Phagocytosis and Proliferation in Adult Hippocampal and SVZ Neural Progenitor Cells: Implications for Inflammation in Neurogenesis
por: Leeson, Hannah C., et al.
Publicado: (2018)

SOX2 Regulates P63 and Stem/Progenitor Cell State in the Corneal Epithelium
por: Bhattacharya, Swarnabh, et al.
Publicado: (2019)

Notch Signaling Regulates the Chondrogenic Potential of Both Articular Chondrocytes and Their Progenitors During Expansion
por: Kurenkova, Anastasiia D, et al.
Publicado: (2023)

Functional Remodeling of Benign Human Prostatic Tissues In Vivo by Spontaneously Immortalized Progenitor and Intermediate Cells
por: Jiang, Ming, et al.
Publicado: (2010)

Inhibition of Platelet-Derived Growth Factor Receptor Signaling Regulates Oct4 and Nanog Expression, Cell Shape, and Mesenchymal Stem Cell Potency
por: Ball, Stephen G, et al.
Publicado: (2012)

Notch Activation Differentially Regulates Renal Progenitors Proliferation and Differentiation Toward the Podocyte Lineage in Glomerular Disorders
por: Lasagni, Laura, et al.
Publicado: (2010)

Role of extracellular vesicles from adipose tissue‐ and bone marrow‐mesenchymal stromal cells in endothelial proliferation and chondrogenesis
por: Gorgun, Cansu, et al.
Publicado: (2021)

National Heart, Lung, and Blood Institute Perspective: Lung Progenitor and Stem Cells—Gaps in Knowledge and Future Opportunities
por: Blaisdell, Carol J, et al.
Publicado: (2009)

Calcium and Calcineurin-NFAT Signaling Regulate Granulocyte-Monocyte Progenitor Cell Cycle via Flt3-L
por: Fric, Jan, et al.
Publicado: (2014)

CRISPR‐Knockout Screen Identifies Dmap1 as a Regulator of Chemically Induced Reprogramming and Differentiation of Cardiac Progenitors
por: Yu, Jason S. L., et al.
Publicado: (2019)

Increased Mitotic Rate Coincident with Transient Telomere Lengthening Resulting from Pim-1 Overexpression in Cardiac Progenitor Cells
por: Cottage, Christopher T, et al.
Publicado: (2012)

CRISPR/Cas9‐Based Dystrophin Restoration Reveals a Novel Role for Dystrophin in Bioenergetics and Stress Resistance of Muscle Progenitors
por: Matre, Polina R., et al.
Publicado: (2019)

TAFA2 Induces Skeletal (Stromal) Stem Cell Migration Through Activation of Rac1‐p38 Signaling
por: Jafari, Abbas, et al.
Publicado: (2018)

Activation of the RhoA‐YAP‐β‐catenin signaling axis promotes the expansion of inner ear progenitor cells in 3D culture
por: Xia, Mingyu, et al.
Publicado: (2020)

Human multipotent adult progenitor cells effectively reduce graft‐vs‐host disease while preserving graft‐vs‐leukemia activity
por: Metheny, Leland, et al.
Publicado: (2021)

FRS2α Regulates Erk Levels to Control a Self-Renewal Target Hes1 and Proliferation of FGF-Responsive Neural Stem/Progenitor Cells
por: Sato, Takuya, et al.
Publicado: (2010)

Characterization of a Fetal Liver Cell Population Endowed with Long‐Term Multiorgan Endothelial Reconstitution Potential
por: Cañete, Ana, et al.
Publicado: (2016)

Uterine Vasculature Remodeling in Human Pregnancy Involves Functional Macrochimerism by Endothelial Colony Forming Cells of Fetal Origin
por: Sipos, Peter I, et al.
Publicado: (2013)

Vascular Stem/Progenitor Cell Migration Induced by Smooth Muscle Cell‐Derived Chemokine (C‐C Motif) Ligand 2 and Chemokine (C‐X‐C motif) Ligand 1 Contributes to Neointima Formation
por: Yu, Baoqi, et al.
Publicado: (2016)

Neural crest‐derived mesenchymal progenitor cells enhance cranial allograft integration
por: Glaeser, Juliane D., et al.
Publicado: (2021)

Characterization of the Effects of Mesenchymal Stromal Cells on Mouse and Human Islet Function
por: Arzouni, Ahmed A., et al.
Publicado: (2019)

Adipogenic Differentiation of Mesenchymal Stem Cells Alters Their Immunomodulatory Properties in a Tissue‐Specific Manner
por: Munir, Hafsa, et al.
Publicado: (2017)

Origin‐Specific Adhesive Interactions of Mesenchymal Stem Cells with Platelets Influence Their Behavior After Infusion
por: Sheriff, Lozan, et al.
Publicado: (2018)

Characterization of Intestinal Mesenchymal Stromal Cells From Patients With Inflammatory Bowel Disease for Autologous Cell Therapy
por: Anbazhagan, Murugadas, et al.
Publicado: (2023)

Alternative splicing in mesenchymal stem cell differentiation
por: Park, Jung Woo, et al.
Publicado: (2020)

The Wnt5a Receptor, Receptor Tyrosine Kinase‐Like Orphan Receptor 2, Is a Predictive Cell Surface Marker of Human Mesenchymal Stem Cells with an Enhanced Capacity for Chondrogenic Differentiation
por: Dickinson, Sally C., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_tute06rm1ev0vr2t1h6bvbgbt1