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Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

Genome-wide association studies, which typically report regression coefficients summarizing the associations of many genetic variants with various traits, are potentially a powerful source of data for Mendelian randomization investigations. We demonstrate how such coefficients from multiple variants...

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Detalles Bibliográficos
Autores principales: Burgess, Stephen, Butterworth, Adam, Thompson, Simon G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377079/
https://www.ncbi.nlm.nih.gov/pubmed/24114802
http://dx.doi.org/10.1002/gepi.21758