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Disseminated histoplasmosis associated with acquired hemophagocytic lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) is a potentially life-threatening clinical syndrome caused by uncontrolled activation of lymphocytes and histiocytes resulting in high levels of cytokines. Acquired HLH occurs in autoimmune, inflammatory, infectious, and immunosuppressive disorders. Prompt id...

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Detalles Bibliográficos
Autores principales: Rajput, Ashish, Bence-Bruckler, Isabelle, Huebsch, Lothar, Jessamine, Peter, Toye, Baldwin, Padmore, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377254/
https://www.ncbi.nlm.nih.gov/pubmed/25838912
http://dx.doi.org/10.1002/ccr3.179
Descripción
Sumario:Hemophagocytic lymphohistiocytosis (HLH) is a potentially life-threatening clinical syndrome caused by uncontrolled activation of lymphocytes and histiocytes resulting in high levels of cytokines. Acquired HLH occurs in autoimmune, inflammatory, infectious, and immunosuppressive disorders. Prompt identification and treatment of an underlying triggering cause improves clinical outcome.