Anticipatory Estrogen Activation of the Unfolded Protein Response is Linked to Cell Proliferation and Poor Survival in Estrogen Receptor α Positive Breast Cancer

In response to cell stress, cancer cells often activate the endoplasmic reticulum (EnR) stress sensor, the unfolded protein response (UPR). Little was known about the potential role in cancer of a different mode of UPR activation; anticipatory activation of the UPR prior to accumulation of unfolded...

Descripción completa

Detalles Bibliográficos
Autores principales: Andruska, Neal, Zheng, Xiaobin, Yang, Xujuan, Helferich, William G., Shapiro, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377305/
https://www.ncbi.nlm.nih.gov/pubmed/25263449
http://dx.doi.org/10.1038/onc.2014.292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377305/
https://www.ncbi.nlm.nih.gov/pubmed/25263449
http://dx.doi.org/10.1038/onc.2014.292

Ejemplares similares