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Anti-leukemic properties of deferasirox via apoptosis in murine leukemia cell lines

BACKGROUND: Although deferasirox (DFX) is reported to have anti-tumor effects, its anti-leukemic activity remains unclear. We evaluated the effect of DFX treatment on two murine lymphoid leukemia cell lines, and clarified the mechanisms underlying its potential anti-leukemic activity. METHODS: L1210...

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Detalles Bibliográficos
Autores principales: Jeon, Sol-Rim, Lee, Jae-Wook, Jang, Pil-Sang, Chung, Nack-Gyun, Cho, Bin, Jeong, Dae-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377336/
https://www.ncbi.nlm.nih.gov/pubmed/25830128
http://dx.doi.org/10.5045/br.2015.50.1.33

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