Cargando…

PTEN Plays an Important Role in Thrombin-Mediated Lung Cancer Cell Functions

Thrombin and its membrane receptor, protease-activated receptor 1 (PAR1), have been reported to promote the development of lung cancer in vitro and in vivo. However, the intracellular molecular mechanism or signaling pathway that mediates the cytological effects after the thrombin-receptor interacti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Zhishan, Zhu, Lingyun, Yao, Min, Zhong, Genshen, Dong, Qiaoyan, Yu, Aiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377361/ https://www.ncbi.nlm.nih.gov/pubmed/25861627 http://dx.doi.org/10.1155/2015/459170

Ejemplares similares

Thrombin Maybe Plays an Important Role in MK Differentiation into Platelets
por: Yang, Xiao-Lei, et al.
Publicado: (2016)

Tobacco Smoke Plays an Important Role in Initiation and Development of Lung Cancer by Promoting the Characteristics of Cancer Stem Cells
por: Lu, Ling, et al.
Publicado: (2020)

The active site region plays a critical role in Na(+) binding to thrombin
por: Pelc, Leslie A., et al.
Publicado: (2021)

The Importance of Thrombin in Cerebral Injury and Disease
por: Krenzlin, Harald, et al.
Publicado: (2016)

Zebrafish pten Genes Play Relevant but Distinct Roles in Antiviral Immunity
por: Pereiro, Patricia, et al.
Publicado: (2020)

Does PTEN gene mutation play any role in Li-Fraumeni syndrome
por: Akouchekian, Mansoureh, et al.
Publicado: (2016)

The Importance of Exosite Interactions for Substrate Cleavage by Human Thrombin
por: Chahal, Gurdeep, et al.
Publicado: (2015)

Thrombin-mediated vasculogenic mimicry: important lessons to improve anticoagulant therapy of selected cancer patients
por: Spek, C. Arnold
Publicado: (2020)

Autophagy may play an important role in varicocele
por: Zhu, Shao-Ming, et al.
Publicado: (2017)

The human complement system in thrombin-mediated platelet function
Publicado: (1978)

ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway
por: Feng, Yubin, et al.
Publicado: (2019)

An arginine-rich cell penetrating peptide contained anti-gelatinase scFv-LDM fusion protein shows potent antitumor efficacy in pancreatic cancer
por: Zhong, Genshen, et al.
Publicado: (2018)

Shikimate Kinase Plays Important Roles in Anthocyanin Synthesis in Petunia
por: Yuan, Junwei, et al.
Publicado: (2022)

Sphingosine Kinase 1 Plays an Important Role in Atorvastatin-Mediated Anti-Inflammatory Effect against Acute Lung Injury
por: Wu, Lan, et al.
Publicado: (2021)

The dishomeostasis of metal ions plays an important role for the cognitive impartment
por: Chui, Dehua, et al.
Publicado: (2013)

The role of thrombin in the pathogenesis of diabetic neuropathy
por: Shavit-Stein, Efrat, et al.
Publicado: (2019)

The role of thrombin in early-onset seizures
por: Savotchenko, Alina, et al.
Publicado: (2023)

NDRG2 plays a pivotal role in ATLL leukaemogenesis by regulating the PTEN-mediated PI3K/AKT signalling pathway
por: Nakahata, Shingo, et al.
Publicado: (2014)

Thrombin functions as an inflammatory mediator through activation of its receptor
Publicado: (1996)

NCAPH plays important roles in human colon cancer
por: Yin, Liang, et al.
Publicado: (2017)

ASXL1 plays an important role in erythropoiesis
por: Shi, Hui, et al.
Publicado: (2016)

Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis
por: Jin, Caixia, et al.
Publicado: (2022)

PTBP1 plays an important role in the development of gastric cancer
por: Chu, Zewen, et al.
Publicado: (2023)

Transarterial oily chemoembolization with lidamycin shows potent therapeutic efficacy in VX2 rabbit liver tumor
por: Zhong, Genshen, et al.
Publicado: (2015)

MiR-130b plays an oncogenic role by repressing PTEN expression in esophageal squamous cell carcinoma cells
por: Yu, Tingting, et al.
Publicado: (2015)

Reproduction of the Solenopsis Mealybug, Phenacoccus Solenopsis: Males Play an Important Role
por: Huang, Fang, et al.
Publicado: (2013)

MicroRNA-221-3p Plays an Oncogenic Role in Gastric Carcinoma by Inhibiting PTEN Expression
por: Shi, Jianping, et al.
Publicado: (2017)

Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration
por: Xu, Meng, et al.
Publicado: (2022)

Neutrophils Play an Important Role in the Recurrence of Chronic Rhinosinusitis with Nasal Polyps
por: Yu, Hyunjae, et al.
Publicado: (2022)

Src activation in the hypothalamic arcuate nucleus may play an important role in pain hypersensitivity
por: Ma, Hanpei, et al.
Publicado: (2019)

Artificial intelligence plays an important role in containing public health emergencies
por: Tang, Ningning, et al.
Publicado: (2020)

Role of thrombin receptor in breast cancer invasiveness
por: Henrikson, K P, et al.
Publicado: (1999)

Snake robots play an important role in social services and military needs
por: Li, Dongfang, et al.
Publicado: (2022)

Regulation of the autophagy plays an important role in acute kidney injury induced acute lung injury
por: Wang, Ruolin, et al.
Publicado: (2022)

Non‐marine turtle plays important functional roles in Indonesian ecosystems
por: Karraker, Nancy E., et al.
Publicado: (2020)

Ataxia-telangiectasia mutated plays an important role in cerebellar integrity and functionality
por: Mitiagin, Yulia, et al.
Publicado: (2022)

Thrombin, a mediator of cerebrovascular inflammation in AD and hypoxia
por: Tripathy, Debjani, et al.
Publicado: (2013)

The transporter GAT1 plays an important role in GABA-mediated carbon-nitrogen interactions in Arabidopsis
por: Batushansky, Albert, et al.
Publicado: (2015)

Splenic responses play an important role in remote ischemic preconditioning-mediated neuroprotection against stroke
por: Chen, Chen, et al.
Publicado: (2018)

PURIFICATION OF THROMBIN
por: Milstone, H.
Publicado: (1942)

Cannot write session to /tmp/vufind_sessions/sess_c0sda31u8i8iqg98fbop9pv0m7