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Medicinal Plants for the Treatment of Hypertrophic Scars
Hypertrophic scar is a complication of wound healing and has a high recurrence rate which can lead to significant abnormity in aesthetics and functions. To date, no ideal treatment method has been established. Meanwhile, the underlying mechanism of hypertrophic scarring has not been clearly defined....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377450/ https://www.ncbi.nlm.nih.gov/pubmed/25861351 http://dx.doi.org/10.1155/2015/101340 |
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author | Ye, Qi Wang, Su-Juan Chen, Jian-Yu Rahman, Khalid Xin, Hai-Liang Zhang, Hong |
author_facet | Ye, Qi Wang, Su-Juan Chen, Jian-Yu Rahman, Khalid Xin, Hai-Liang Zhang, Hong |
author_sort | Ye, Qi |
collection | PubMed |
description | Hypertrophic scar is a complication of wound healing and has a high recurrence rate which can lead to significant abnormity in aesthetics and functions. To date, no ideal treatment method has been established. Meanwhile, the underlying mechanism of hypertrophic scarring has not been clearly defined. Although a large amount of scientific research has been reported on the use of medicinal plants as a natural source of treatment for hypertrophic scarring, it is currently scattered across a wide range of publications. Therefore, a systematic summary and knowledge for future prospects are necessary to facilitate further medicinal plant research for their potential use as antihypertrophic scar agents. A bibliographic investigation was accomplished by focusing on medicinal plants which have been scientifically tested in vitro and/or in vivo and proved as potential agents for the treatment of hypertrophic scars. Although the chemical components and mechanisms of action of medicinal plants with antihypertrophic scarring potential have been investigated, many others remain unknown. More investigations and clinical trials are necessary to make use of these medical plants reasonably and phytotherapy is a promising therapeutic approach against hypertrophic scars. |
format | Online Article Text |
id | pubmed-4377450 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43774502015-04-08 Medicinal Plants for the Treatment of Hypertrophic Scars Ye, Qi Wang, Su-Juan Chen, Jian-Yu Rahman, Khalid Xin, Hai-Liang Zhang, Hong Evid Based Complement Alternat Med Review Article Hypertrophic scar is a complication of wound healing and has a high recurrence rate which can lead to significant abnormity in aesthetics and functions. To date, no ideal treatment method has been established. Meanwhile, the underlying mechanism of hypertrophic scarring has not been clearly defined. Although a large amount of scientific research has been reported on the use of medicinal plants as a natural source of treatment for hypertrophic scarring, it is currently scattered across a wide range of publications. Therefore, a systematic summary and knowledge for future prospects are necessary to facilitate further medicinal plant research for their potential use as antihypertrophic scar agents. A bibliographic investigation was accomplished by focusing on medicinal plants which have been scientifically tested in vitro and/or in vivo and proved as potential agents for the treatment of hypertrophic scars. Although the chemical components and mechanisms of action of medicinal plants with antihypertrophic scarring potential have been investigated, many others remain unknown. More investigations and clinical trials are necessary to make use of these medical plants reasonably and phytotherapy is a promising therapeutic approach against hypertrophic scars. Hindawi Publishing Corporation 2015 2015-03-11 /pmc/articles/PMC4377450/ /pubmed/25861351 http://dx.doi.org/10.1155/2015/101340 Text en Copyright © 2015 Qi Ye et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Ye, Qi Wang, Su-Juan Chen, Jian-Yu Rahman, Khalid Xin, Hai-Liang Zhang, Hong Medicinal Plants for the Treatment of Hypertrophic Scars |
title | Medicinal Plants for the Treatment of Hypertrophic Scars |
title_full | Medicinal Plants for the Treatment of Hypertrophic Scars |
title_fullStr | Medicinal Plants for the Treatment of Hypertrophic Scars |
title_full_unstemmed | Medicinal Plants for the Treatment of Hypertrophic Scars |
title_short | Medicinal Plants for the Treatment of Hypertrophic Scars |
title_sort | medicinal plants for the treatment of hypertrophic scars |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377450/ https://www.ncbi.nlm.nih.gov/pubmed/25861351 http://dx.doi.org/10.1155/2015/101340 |
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