Cargando…

Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research

Over the years, cell therapy has become an exciting opportunity to treat human diseases. Early enthusiasm using adult stem cell sources has been tempered in light of preliminary benefits in patients. Considerable efforts have been dedicated, therefore, to explore alternative cells such as those extr...

Descripción completa

Detalles Bibliográficos
Autores principales: Roura, Santiago, Pujal, Josep Maria, Gálvez-Montón, Carolina, Bayes-Genis, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377460/
https://www.ncbi.nlm.nih.gov/pubmed/25861654
http://dx.doi.org/10.1155/2015/975302
_version_ 1782363914565058560
author Roura, Santiago
Pujal, Josep Maria
Gálvez-Montón, Carolina
Bayes-Genis, Antoni
author_facet Roura, Santiago
Pujal, Josep Maria
Gálvez-Montón, Carolina
Bayes-Genis, Antoni
author_sort Roura, Santiago
collection PubMed
description Over the years, cell therapy has become an exciting opportunity to treat human diseases. Early enthusiasm using adult stem cell sources has been tempered in light of preliminary benefits in patients. Considerable efforts have been dedicated, therefore, to explore alternative cells such as those extracted from umbilical cord blood (UCB). In line, UCB banking has become a popular possibility to preserve potentially life-saving cells that are usually discarded after birth, and the number of UCB banks has grown worldwide. Thus, a brief overview on the categories of UCB banks as well as the properties, challenges, and impact of UCB-derived mesenchymal stem cells (MSCs) on the area of cardiovascular research is presented. Taken together, the experience recounted here shows that UCBMSCs are envisioned as attractive therapeutic candidates against human disorders arising and/or progressing with vascular deficit.
format Online
Article
Text
id pubmed-4377460
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-43774602015-04-08 Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research Roura, Santiago Pujal, Josep Maria Gálvez-Montón, Carolina Bayes-Genis, Antoni Biomed Res Int Review Article Over the years, cell therapy has become an exciting opportunity to treat human diseases. Early enthusiasm using adult stem cell sources has been tempered in light of preliminary benefits in patients. Considerable efforts have been dedicated, therefore, to explore alternative cells such as those extracted from umbilical cord blood (UCB). In line, UCB banking has become a popular possibility to preserve potentially life-saving cells that are usually discarded after birth, and the number of UCB banks has grown worldwide. Thus, a brief overview on the categories of UCB banks as well as the properties, challenges, and impact of UCB-derived mesenchymal stem cells (MSCs) on the area of cardiovascular research is presented. Taken together, the experience recounted here shows that UCBMSCs are envisioned as attractive therapeutic candidates against human disorders arising and/or progressing with vascular deficit. Hindawi Publishing Corporation 2015 2015-03-10 /pmc/articles/PMC4377460/ /pubmed/25861654 http://dx.doi.org/10.1155/2015/975302 Text en Copyright © 2015 Santiago Roura et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Roura, Santiago
Pujal, Josep Maria
Gálvez-Montón, Carolina
Bayes-Genis, Antoni
Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research
title Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research
title_full Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research
title_fullStr Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research
title_full_unstemmed Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research
title_short Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research
title_sort impact of umbilical cord blood-derived mesenchymal stem cells on cardiovascular research
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377460/
https://www.ncbi.nlm.nih.gov/pubmed/25861654
http://dx.doi.org/10.1155/2015/975302
work_keys_str_mv AT rourasantiago impactofumbilicalcordbloodderivedmesenchymalstemcellsoncardiovascularresearch
AT pujaljosepmaria impactofumbilicalcordbloodderivedmesenchymalstemcellsoncardiovascularresearch
AT galvezmontoncarolina impactofumbilicalcordbloodderivedmesenchymalstemcellsoncardiovascularresearch
AT bayesgenisantoni impactofumbilicalcordbloodderivedmesenchymalstemcellsoncardiovascularresearch