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Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research
Over the years, cell therapy has become an exciting opportunity to treat human diseases. Early enthusiasm using adult stem cell sources has been tempered in light of preliminary benefits in patients. Considerable efforts have been dedicated, therefore, to explore alternative cells such as those extr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377460/ https://www.ncbi.nlm.nih.gov/pubmed/25861654 http://dx.doi.org/10.1155/2015/975302 |
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author | Roura, Santiago Pujal, Josep Maria Gálvez-Montón, Carolina Bayes-Genis, Antoni |
author_facet | Roura, Santiago Pujal, Josep Maria Gálvez-Montón, Carolina Bayes-Genis, Antoni |
author_sort | Roura, Santiago |
collection | PubMed |
description | Over the years, cell therapy has become an exciting opportunity to treat human diseases. Early enthusiasm using adult stem cell sources has been tempered in light of preliminary benefits in patients. Considerable efforts have been dedicated, therefore, to explore alternative cells such as those extracted from umbilical cord blood (UCB). In line, UCB banking has become a popular possibility to preserve potentially life-saving cells that are usually discarded after birth, and the number of UCB banks has grown worldwide. Thus, a brief overview on the categories of UCB banks as well as the properties, challenges, and impact of UCB-derived mesenchymal stem cells (MSCs) on the area of cardiovascular research is presented. Taken together, the experience recounted here shows that UCBMSCs are envisioned as attractive therapeutic candidates against human disorders arising and/or progressing with vascular deficit. |
format | Online Article Text |
id | pubmed-4377460 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43774602015-04-08 Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research Roura, Santiago Pujal, Josep Maria Gálvez-Montón, Carolina Bayes-Genis, Antoni Biomed Res Int Review Article Over the years, cell therapy has become an exciting opportunity to treat human diseases. Early enthusiasm using adult stem cell sources has been tempered in light of preliminary benefits in patients. Considerable efforts have been dedicated, therefore, to explore alternative cells such as those extracted from umbilical cord blood (UCB). In line, UCB banking has become a popular possibility to preserve potentially life-saving cells that are usually discarded after birth, and the number of UCB banks has grown worldwide. Thus, a brief overview on the categories of UCB banks as well as the properties, challenges, and impact of UCB-derived mesenchymal stem cells (MSCs) on the area of cardiovascular research is presented. Taken together, the experience recounted here shows that UCBMSCs are envisioned as attractive therapeutic candidates against human disorders arising and/or progressing with vascular deficit. Hindawi Publishing Corporation 2015 2015-03-10 /pmc/articles/PMC4377460/ /pubmed/25861654 http://dx.doi.org/10.1155/2015/975302 Text en Copyright © 2015 Santiago Roura et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Roura, Santiago Pujal, Josep Maria Gálvez-Montón, Carolina Bayes-Genis, Antoni Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research |
title | Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research |
title_full | Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research |
title_fullStr | Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research |
title_full_unstemmed | Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research |
title_short | Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research |
title_sort | impact of umbilical cord blood-derived mesenchymal stem cells on cardiovascular research |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377460/ https://www.ncbi.nlm.nih.gov/pubmed/25861654 http://dx.doi.org/10.1155/2015/975302 |
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