Genome-Wide Expression of MicroRNAs Is Regulated by DNA Methylation in Hepatocarcinogenesis

Background. Previous studies, including ours, have examined the regulation of microRNAs (miRNAs) by DNA methylation, but whether this regulation occurs at a genome-wide level in hepatocellular carcinoma (HCC) is unclear. Subjects/Methods. Using a two-phase study design, we conducted genome-wide scre...

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Detalles Bibliográficos
Autores principales: Shen, Jing, Wang, Shuang, Siegel, Abby B., Remotti, Helen, Wang, Qiao, Sirosh, Iryna, Santella, Regina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377534/
https://www.ncbi.nlm.nih.gov/pubmed/25861255
http://dx.doi.org/10.1155/2015/230642

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