Inducible VEGF Expression by Human Embryonic Stem Cell-Derived Mesenchymal Stromal Cells Reduces the Minimal Islet Mass Required to Reverse Diabetes

Islet transplantation has been hampered by loss of function due to poor revascularization. We hypothesize that co-transplantation of islets with human embryonic stem cell-derived mesenchymal stromal cells that conditionally overexpress VEGF (hESC-MSC:VEGF) may augment islet revascularization and red...

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Detalles Bibliográficos
Autores principales: Hajizadeh-Saffar, E., Tahamtani, Y., Aghdami, N., Azadmanesh, K., Habibi-Anbouhi, M., Heremans, Y., De Leu, N., Heimberg, H., Ravassard, P., Shokrgozar, M. A., Baharvand, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377549/
https://www.ncbi.nlm.nih.gov/pubmed/25818803
http://dx.doi.org/10.1038/srep09322

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