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Uncovering pharmacological mechanisms of Wu-tou decoction acting on rheumatoid arthritis through systems approaches: drug-target prediction, network analysis and experimental validation
Wu-tou decoction (WTD) has been extensively used for the treatment of rheumatoid arthritis (RA). Due to lack of appropriate methods, pharmacological mechanisms of WTD acting on RA have not been fully elucidated. In this study, a list of putative targets for compositive compounds containing in WTD we...
Autores principales: | Zhang, Yanqiong, Bai, Ming, Zhang, Bo, Liu, Chunfang, Guo, Qiuyan, Sun, Yanqun, Wang, Danhua, Wang, Chao, Jiang, Yini, Lin, Na, Li, Shao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377576/ https://www.ncbi.nlm.nih.gov/pubmed/25820382 http://dx.doi.org/10.1038/srep09463 |
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