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Uncovering pharmacological mechanisms of Wu-tou decoction acting on rheumatoid arthritis through systems approaches: drug-target prediction, network analysis and experimental validation

Wu-tou decoction (WTD) has been extensively used for the treatment of rheumatoid arthritis (RA). Due to lack of appropriate methods, pharmacological mechanisms of WTD acting on RA have not been fully elucidated. In this study, a list of putative targets for compositive compounds containing in WTD we...

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Detalles Bibliográficos
Autores principales: Zhang, Yanqiong, Bai, Ming, Zhang, Bo, Liu, Chunfang, Guo, Qiuyan, Sun, Yanqun, Wang, Danhua, Wang, Chao, Jiang, Yini, Lin, Na, Li, Shao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377576/
https://www.ncbi.nlm.nih.gov/pubmed/25820382
http://dx.doi.org/10.1038/srep09463

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