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Radionuclide Imaging of Neurohormonal System of the Heart

Heart failure is one of the growing causes of death especially in developed countries due to longer life expectancy. Although many pharmacological and instrumental therapeutic approaches have been introduced for prevention and treatment of heart failure, there are still limitations and challenges. N...

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Autores principales: Chen, Xinyu, Werner, Rudolf A., Javadi, Mehrbod S., Maya, Yoshifumi, Decker, Michael, Lapa, Constantin, Herrmann, Ken, Higuchi, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377725/
https://www.ncbi.nlm.nih.gov/pubmed/25825596
http://dx.doi.org/10.7150/thno.10900
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author Chen, Xinyu
Werner, Rudolf A.
Javadi, Mehrbod S.
Maya, Yoshifumi
Decker, Michael
Lapa, Constantin
Herrmann, Ken
Higuchi, Takahiro
author_facet Chen, Xinyu
Werner, Rudolf A.
Javadi, Mehrbod S.
Maya, Yoshifumi
Decker, Michael
Lapa, Constantin
Herrmann, Ken
Higuchi, Takahiro
author_sort Chen, Xinyu
collection PubMed
description Heart failure is one of the growing causes of death especially in developed countries due to longer life expectancy. Although many pharmacological and instrumental therapeutic approaches have been introduced for prevention and treatment of heart failure, there are still limitations and challenges. Nuclear cardiology has experienced rapid growth in the last few decades, in particular the application of single photon emission computed tomography (SPECT) and positron emission tomography (PET), which allow non-invasive functional assessment of cardiac condition including neurohormonal systems involved in heart failure; its application has dramatically improved the capacity for fundamental research and clinical diagnosis. In this article, we review the current status of applying radionuclide technology in non-invasive imaging of neurohormonal system in the heart, especially focusing on the tracers that are currently available. A short discussion about disadvantages and perspectives is also included.
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spelling pubmed-43777252015-03-30 Radionuclide Imaging of Neurohormonal System of the Heart Chen, Xinyu Werner, Rudolf A. Javadi, Mehrbod S. Maya, Yoshifumi Decker, Michael Lapa, Constantin Herrmann, Ken Higuchi, Takahiro Theranostics Review Heart failure is one of the growing causes of death especially in developed countries due to longer life expectancy. Although many pharmacological and instrumental therapeutic approaches have been introduced for prevention and treatment of heart failure, there are still limitations and challenges. Nuclear cardiology has experienced rapid growth in the last few decades, in particular the application of single photon emission computed tomography (SPECT) and positron emission tomography (PET), which allow non-invasive functional assessment of cardiac condition including neurohormonal systems involved in heart failure; its application has dramatically improved the capacity for fundamental research and clinical diagnosis. In this article, we review the current status of applying radionuclide technology in non-invasive imaging of neurohormonal system in the heart, especially focusing on the tracers that are currently available. A short discussion about disadvantages and perspectives is also included. Ivyspring International Publisher 2015-02-15 /pmc/articles/PMC4377725/ /pubmed/25825596 http://dx.doi.org/10.7150/thno.10900 Text en © 2015 Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. Please see http://ivyspring.com/terms for terms and conditions.
spellingShingle Review
Chen, Xinyu
Werner, Rudolf A.
Javadi, Mehrbod S.
Maya, Yoshifumi
Decker, Michael
Lapa, Constantin
Herrmann, Ken
Higuchi, Takahiro
Radionuclide Imaging of Neurohormonal System of the Heart
title Radionuclide Imaging of Neurohormonal System of the Heart
title_full Radionuclide Imaging of Neurohormonal System of the Heart
title_fullStr Radionuclide Imaging of Neurohormonal System of the Heart
title_full_unstemmed Radionuclide Imaging of Neurohormonal System of the Heart
title_short Radionuclide Imaging of Neurohormonal System of the Heart
title_sort radionuclide imaging of neurohormonal system of the heart
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377725/
https://www.ncbi.nlm.nih.gov/pubmed/25825596
http://dx.doi.org/10.7150/thno.10900
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