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Radionuclide Imaging of Neurohormonal System of the Heart
Heart failure is one of the growing causes of death especially in developed countries due to longer life expectancy. Although many pharmacological and instrumental therapeutic approaches have been introduced for prevention and treatment of heart failure, there are still limitations and challenges. N...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377725/ https://www.ncbi.nlm.nih.gov/pubmed/25825596 http://dx.doi.org/10.7150/thno.10900 |
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author | Chen, Xinyu Werner, Rudolf A. Javadi, Mehrbod S. Maya, Yoshifumi Decker, Michael Lapa, Constantin Herrmann, Ken Higuchi, Takahiro |
author_facet | Chen, Xinyu Werner, Rudolf A. Javadi, Mehrbod S. Maya, Yoshifumi Decker, Michael Lapa, Constantin Herrmann, Ken Higuchi, Takahiro |
author_sort | Chen, Xinyu |
collection | PubMed |
description | Heart failure is one of the growing causes of death especially in developed countries due to longer life expectancy. Although many pharmacological and instrumental therapeutic approaches have been introduced for prevention and treatment of heart failure, there are still limitations and challenges. Nuclear cardiology has experienced rapid growth in the last few decades, in particular the application of single photon emission computed tomography (SPECT) and positron emission tomography (PET), which allow non-invasive functional assessment of cardiac condition including neurohormonal systems involved in heart failure; its application has dramatically improved the capacity for fundamental research and clinical diagnosis. In this article, we review the current status of applying radionuclide technology in non-invasive imaging of neurohormonal system in the heart, especially focusing on the tracers that are currently available. A short discussion about disadvantages and perspectives is also included. |
format | Online Article Text |
id | pubmed-4377725 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-43777252015-03-30 Radionuclide Imaging of Neurohormonal System of the Heart Chen, Xinyu Werner, Rudolf A. Javadi, Mehrbod S. Maya, Yoshifumi Decker, Michael Lapa, Constantin Herrmann, Ken Higuchi, Takahiro Theranostics Review Heart failure is one of the growing causes of death especially in developed countries due to longer life expectancy. Although many pharmacological and instrumental therapeutic approaches have been introduced for prevention and treatment of heart failure, there are still limitations and challenges. Nuclear cardiology has experienced rapid growth in the last few decades, in particular the application of single photon emission computed tomography (SPECT) and positron emission tomography (PET), which allow non-invasive functional assessment of cardiac condition including neurohormonal systems involved in heart failure; its application has dramatically improved the capacity for fundamental research and clinical diagnosis. In this article, we review the current status of applying radionuclide technology in non-invasive imaging of neurohormonal system in the heart, especially focusing on the tracers that are currently available. A short discussion about disadvantages and perspectives is also included. Ivyspring International Publisher 2015-02-15 /pmc/articles/PMC4377725/ /pubmed/25825596 http://dx.doi.org/10.7150/thno.10900 Text en © 2015 Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. Please see http://ivyspring.com/terms for terms and conditions. |
spellingShingle | Review Chen, Xinyu Werner, Rudolf A. Javadi, Mehrbod S. Maya, Yoshifumi Decker, Michael Lapa, Constantin Herrmann, Ken Higuchi, Takahiro Radionuclide Imaging of Neurohormonal System of the Heart |
title | Radionuclide Imaging of Neurohormonal System of the Heart |
title_full | Radionuclide Imaging of Neurohormonal System of the Heart |
title_fullStr | Radionuclide Imaging of Neurohormonal System of the Heart |
title_full_unstemmed | Radionuclide Imaging of Neurohormonal System of the Heart |
title_short | Radionuclide Imaging of Neurohormonal System of the Heart |
title_sort | radionuclide imaging of neurohormonal system of the heart |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377725/ https://www.ncbi.nlm.nih.gov/pubmed/25825596 http://dx.doi.org/10.7150/thno.10900 |
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