Renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine

Quinine has been reported to cause acute kidney injury by various mechanisms. The response to quinine can result in a spectrum of problems ranging from isolated thrombocytopenia to thrombotic microangiopathy (TMA) to disseminated intravascular coagulation. Quinine has also been reported to cause acu...

Descripción completa

Detalles Bibliográficos
Autores principales: Anjelo, Jobert, Rao, Nitesh, David, Vinoi G., Otto, Sophia, Russ, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Clinical Cases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377755/
https://www.ncbi.nlm.nih.gov/pubmed/25852897
http://dx.doi.org/10.1093/ckj/sfu035
Descripción
Sumario:Quinine has been reported to cause acute kidney injury by various mechanisms. The response to quinine can result in a spectrum of problems ranging from isolated thrombocytopenia to thrombotic microangiopathy (TMA) to disseminated intravascular coagulation. Quinine has also been reported to cause acute interstitial nephritis (AIN). We report an unusual presentation where both of these entities of renal-limited TMA and AIN were precipitated by a single dose of quinine.

Ejemplares similares