Renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine

Quinine has been reported to cause acute kidney injury by various mechanisms. The response to quinine can result in a spectrum of problems ranging from isolated thrombocytopenia to thrombotic microangiopathy (TMA) to disseminated intravascular coagulation. Quinine has also been reported to cause acu...

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Autores principales: Anjelo, Jobert, Rao, Nitesh, David, Vinoi G., Otto, Sophia, Russ, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Clinical Cases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377755/
https://www.ncbi.nlm.nih.gov/pubmed/25852897
http://dx.doi.org/10.1093/ckj/sfu035
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author Anjelo, Jobert
Rao, Nitesh
David, Vinoi G.
Otto, Sophia
Russ, Graeme
author_facet Anjelo, Jobert
Rao, Nitesh
David, Vinoi G.
Otto, Sophia
Russ, Graeme
author_sort Anjelo, Jobert
collection PubMed
description Quinine has been reported to cause acute kidney injury by various mechanisms. The response to quinine can result in a spectrum of problems ranging from isolated thrombocytopenia to thrombotic microangiopathy (TMA) to disseminated intravascular coagulation. Quinine has also been reported to cause acute interstitial nephritis (AIN). We report an unusual presentation where both of these entities of renal-limited TMA and AIN were precipitated by a single dose of quinine.
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spelling pubmed-43777552015-04-07 Renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine Anjelo, Jobert Rao, Nitesh David, Vinoi G. Otto, Sophia Russ, Graeme Clin Kidney J Clinical Cases Quinine has been reported to cause acute kidney injury by various mechanisms. The response to quinine can result in a spectrum of problems ranging from isolated thrombocytopenia to thrombotic microangiopathy (TMA) to disseminated intravascular coagulation. Quinine has also been reported to cause acute interstitial nephritis (AIN). We report an unusual presentation where both of these entities of renal-limited TMA and AIN were precipitated by a single dose of quinine. Oxford University Press 2014-06 2014-05-07 /pmc/articles/PMC4377755/ /pubmed/25852897 http://dx.doi.org/10.1093/ckj/sfu035 Text en © The Author 2014. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For permissions, please email: journals.permissions@oup.com. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Clinical Cases
Anjelo, Jobert
Rao, Nitesh
David, Vinoi G.
Otto, Sophia
Russ, Graeme
Renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine
title Renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine
title_full Renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine
title_fullStr Renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine
title_full_unstemmed Renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine
title_short Renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine
title_sort renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine
topic Clinical Cases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377755/
https://www.ncbi.nlm.nih.gov/pubmed/25852897
http://dx.doi.org/10.1093/ckj/sfu035
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