High-resolution genomic analysis: the tumor-immune interface comes into focus

A genomic analysis of heterogeneous colorectal tumor samples has uncovered interactions between immunophenotype and various aspects of tumor biology, with implications for informing the choice of immunotherapies for specific patients and guiding the design of personalized neoantigen-based vaccines....

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Detalles Bibliográficos
Autores principales: Havel, Jonathan J, Chan, Timothy A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377855/
https://www.ncbi.nlm.nih.gov/pubmed/25853850
http://dx.doi.org/10.1186/s13059-015-0631-3
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author Havel, Jonathan J
Chan, Timothy A
author_facet Havel, Jonathan J
Chan, Timothy A
author_sort Havel, Jonathan J
collection PubMed
description A genomic analysis of heterogeneous colorectal tumor samples has uncovered interactions between immunophenotype and various aspects of tumor biology, with implications for informing the choice of immunotherapies for specific patients and guiding the design of personalized neoantigen-based vaccines. Please see related article: http://dx.doi.org/10.1186/s13059-015-0620-6
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spelling pubmed-43778552015-03-31 High-resolution genomic analysis: the tumor-immune interface comes into focus Havel, Jonathan J Chan, Timothy A Genome Biol Research Highlight A genomic analysis of heterogeneous colorectal tumor samples has uncovered interactions between immunophenotype and various aspects of tumor biology, with implications for informing the choice of immunotherapies for specific patients and guiding the design of personalized neoantigen-based vaccines. Please see related article: http://dx.doi.org/10.1186/s13059-015-0620-6 BioMed Central 2015-03-31 2015 /pmc/articles/PMC4377855/ /pubmed/25853850 http://dx.doi.org/10.1186/s13059-015-0631-3 Text en © Havel and Chan; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Highlight
Havel, Jonathan J
Chan, Timothy A
High-resolution genomic analysis: the tumor-immune interface comes into focus
title High-resolution genomic analysis: the tumor-immune interface comes into focus
title_full High-resolution genomic analysis: the tumor-immune interface comes into focus
title_fullStr High-resolution genomic analysis: the tumor-immune interface comes into focus
title_full_unstemmed High-resolution genomic analysis: the tumor-immune interface comes into focus
title_short High-resolution genomic analysis: the tumor-immune interface comes into focus
title_sort high-resolution genomic analysis: the tumor-immune interface comes into focus
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377855/
https://www.ncbi.nlm.nih.gov/pubmed/25853850
http://dx.doi.org/10.1186/s13059-015-0631-3
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