Cargando…

Anticancer Activity of Sea Cucumber Triterpene Glycosides

Triterpene glycosides are characteristic secondary metabolites of sea cucumbers (Holothurioidea, Echinodermata). They have hemolytic, cytotoxic, antifungal, and other biological activities caused by membranotropic action. These natural products suppress the proliferation of various human tumor cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aminin, Dmitry L., Menchinskaya, Ekaterina S., Pisliagin, Evgeny A., Silchenko, Alexandra S., Avilov, Sergey A., Kalinin, Vladimir I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377980/ https://www.ncbi.nlm.nih.gov/pubmed/25756523 http://dx.doi.org/10.3390/md13031202

Ejemplares similares

Modulation of Doxorubicin Intracellular Accumulation and Anticancer Activity by Triterpene Glycoside Cucumarioside A(2)-2
por: Menchinskaya, Ekaterina, et al.
Publicado: (2019)

A Mass Spectrometry Database for Sea Cucumber Triterpene Glycosides
por: Popov, Roman S., et al.
Publicado: (2023)

Chilensosides E, F, and G—New Tetrasulfated Triterpene Glycosides from the Sea Cucumber Paracaudina chilensis (Caudinidae, Molpadida): Structures, Activity, and Biogenesis
por: Silchenko, Alexandra S., et al.
Publicado: (2023)

Triterpene Glycosides from the Far Eastern Sea Cucumber Psolus chitonoides: Chemical Structures and Cytotoxicities of Chitonoidosides E(1), F, G, and H
por: Silchenko, Alexandra S., et al.
Publicado: (2021)

Unusual Structures and Cytotoxicities of Chitonoidosides A, A(1), B, C, D, and E, Six Triterpene Glycosides from the Far Eastern Sea Cucumber Psolus chitonoides
por: Silchenko, Alexandra S., et al.
Publicado: (2021)

Metabolite Profiling of Triterpene Glycosides of the Far Eastern Sea Cucumber Eupentacta fraudatrix and Their Distribution in Various Body Components Using LC-ESI QTOF-MS
por: Popov, Roman S., et al.
Publicado: (2017)

Structures and Biogenesis of Fallaxosides D(4), D(5), D(6) and D(7), Trisulfated Non-Holostane Triterpene Glycosides from the Sea Cucumber Cucumaria fallax
por: Silchenko, Alexandra S., et al.
Publicado: (2016)

Holothurian triterpene glycoside cucumarioside A(2)-2 induces macrophages activation and polarization in cancer immunotherapy
por: Chuang, Wen-Han, et al.
Publicado: (2023)

Kurilosides A(1), A(2), C(1), D, E and F—Triterpene Glycosides from the Far Eastern Sea Cucumber Thyonidium (= Duasmodactyla) kurilensis (Levin): Structures with Unusual Non-Holostane Aglycones and Cytotoxicities
por: Silchenko, Alexandra S., et al.
Publicado: (2020)

Structures and Bioactivities of Six New Triterpene Glycosides, Psolusosides E, F, G, H, H(1), and I and the Corrected Structure of Psolusoside B from the Sea Cucumber Psolus fabricii
por: Silchenko, Alexandra S., et al.
Publicado: (2019)

Structure-Activity Relationships of Holothuroid’s Triterpene Glycosides and Some In Silico Insights Obtained by Molecular Dynamics Study on the Mechanisms of Their Membranolytic Action
por: Zelepuga, Elena A., et al.
Publicado: (2021)

Triterpene Glycosides from the Far Eastern Sea Cucumber Thyonidium (=Duasmodactyla) kurilensis (Levin): The Structures, Cytotoxicities, and Biogenesis of Kurilosides A(3), D(1), G, H, I, I(1), J, K, and K(1)
por: Silchenko, Alexandra S., et al.
Publicado: (2021)

Structures and Biologic Activity of Chitonoidosides I, J, K, K(1) and L-Triterpene Di-, Tri- and Tetrasulfated Hexaosides from the Sea Cucumber Psolus chitonoides
por: Silchenko, Alexandra S., et al.
Publicado: (2022)

Djakonoviosides A, A(1), A(2), B(1)–B(4) — Triterpene Monosulfated Tetra- and Pentaosides from the Sea Cucumber Cucumaria djakonovi: The First Finding of a Hemiketal Fragment in the Aglycones; Activity against Human Breast Cancer Cell Lines
por: Silchenko, Alexandra S., et al.
Publicado: (2023)

Glycosides from edible sea cucumbers stimulate macrophages via purinergic receptors
por: Aminin, Dmitry, et al.
Publicado: (2016)

The Isolation, Structure Elucidation and Bioactivity Study of Chilensosides A, A(1), B, C, and D, Holostane Triterpene Di-, Tri- and Tetrasulfated Pentaosides from the Sea Cucumber Paracaudina chilensis (Caudinidae, Molpadida)
por: Silchenko, Alexandra S., et al.
Publicado: (2022)

Nine New Triterpene Glycosides, Magnumosides A(1)–A(4), B(1), B(2), C(1), C(2) and C(4), from the Vietnamese Sea Cucumber Neothyonidium (=Massinium) magnum: Structures and Activities against Tumor Cells Independently and in Synergy with Radioactive Irradiation
por: Silchenko, Alexandra S., et al.
Publicado: (2017)

The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2017)

Synthesis, Cytotoxic Activity Evaluation and Quantitative Structure-ActivityAnalysis of Substituted 5,8-Dihydroxy-1,4-naphthoquinones and Their O- and S-Glycoside Derivatives Tested against Neuro-2a Cancer Cells
por: Polonik, Sergey, et al.
Publicado: (2020)

Relationships between chemical structures and functions of triterpene glycosides isolated from sea cucumbers
por: Park, Joo-In, et al.
Publicado: (2014)

Structures and Bioactivities of Quadrangularisosides A, A(1), B, B(1), B(2), C, C(1), D, D(1)–D(4), and E from the Sea Cucumber Colochirus quadrangularis: The First Discovery of the Glycosides, Sulfated by C-4 of the Terminal 3-O-Methylglucose Residue. Synergetic Effect on Colony Formation of Tumor HT-29 Cells of these Glycosides with Radioactive Irradiation
por: Silchenko, Alexandra S., et al.
Publicado: (2020)

Structures and Bioactivities of Psolusosides B(1), B(2), J, K, L, M, N, O, P, and Q from the Sea Cucumber Psolus fabricii. The First Finding of Tetrasulfated Marine Low Molecular Weight Metabolites
por: Silchenko, Alexandra S., et al.
Publicado: (2019)

Variegatusides: New Non-Sulphated Triterpene Glycosides from the Sea Cucumber Stichopus variegates Semper
por: Wang, Xiao-Hua, et al.
Publicado: (2014)

Corrigendum: Relationships between chemical structures and functions of triterpene glycosides isolated from sea cucumbers
por: Kwak, Jong-Young
Publicado: (2014)

Cucumarioside A(2)-2 Causes Macrophage Activation in Mouse Spleen
por: Pislyagin, Evgeny A., et al.
Publicado: (2017)

Saponin and Fatty Acid Profiling of the Sea Cucumber Holothuria atra, α-Glucosidase Inhibitory Activity and the Identification of a Novel Triterpene Glycoside
por: Puspitasari, Yunita Eka, et al.
Publicado: (2023)

Triterpene and Steroid Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological Activities
por: Ivanchina, Natalia V., et al.
Publicado: (2023)

Sea Anemone Kunitz-Type Peptides Demonstrate Neuroprotective Activity in the 6-Hydroxydopamine Induced Neurotoxicity Model
por: Sintsova, Oksana, et al.
Publicado: (2021)

Neuroprotective Effect of 1,4-Naphthoquinones in an In Vitro Model of Paraquat and 6-OHDA-Induced Neurotoxicity
por: Menchinskaya, Ekaterina, et al.
Publicado: (2021)

In Vitro Anticancer and Cancer-Preventive Activity of New Triterpene Glycosides from the Far Eastern Starfish Solaster pacificus
por: Malyarenko, Timofey V., et al.
Publicado: (2022)

Anti-Inflammatory Activity of 1,4-Naphthoquinones Blocking P2X7 Purinergic Receptors in RAW 264.7 Macrophage Cells
por: Kozlovskiy, Sergei A., et al.
Publicado: (2023)

Lanostane Triterpenoid Metabolites from a Penares sp. Marine Sponge Protect Neuro-2a Cells against Paraquat Neurotoxicity
por: Yurchenko, Ekaterina A., et al.
Publicado: (2020)

Sea Cucumber Glycosides: Chemical Structures, Producing Species and Important Biological Properties
por: Mondol, Muhammad Abdul Mojid, et al.
Publicado: (2017)

Fucosylated Chondroitin Sulfates from the Sea Cucumbers Paracaudina chilensis and Holothuria hilla: Structures and Anticoagulant Activity
por: Ustyuzhanina, Nadezhda E., et al.
Publicado: (2020)

New Triterpene Glycosides from the Far Eastern Starfish Solaster pacificus and Their Biological Activity
por: Malyarenko, Timofey V., et al.
Publicado: (2021)

Cytoprotective Activity of p-Terphenyl Polyketides and Flavuside B from Marine-Derived Fungi against Oxidative Stress in Neuro-2a Cells
por: Yurchenko, Ekaterina A., et al.
Publicado: (2021)

Tetracyclic 1,4-Naphthoquinone Thioglucoside Conjugate U-556 Blocks the Purinergic P2X7 Receptor in Macrophages and Exhibits Anti-Inflammatory Activity In Vivo
por: Kozlovskiy, Sergei, et al.
Publicado: (2023)

Azukisapogenol Triterpene Glycosides from Oxytropis chiliophylla Royle
por: Wang, Jun, et al.
Publicado: (2018)

A new multigene HCIQ subfamily from the sea anemone Heteractis crispa encodes Kunitz-peptides exhibiting neuroprotective activity against 6-hydroxydopamine
por: Kvetkina, Aleksandra, et al.
Publicado: (2020)

Kunitz-Type Peptides from Sea Anemones Protect Neuronal Cells against Parkinson’s Disease Inductors via Inhibition of ROS Production and ATP-Induced P2X7 Receptor Activation
por: Kvetkina, Aleksandra, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_l9dgijrsv8qdpvcqi4526500ja