Viral noncoding RNAs: more surprises

Eukaryotic cells produce several classes of long and small noncoding RNA (ncRNA). Many DNA and RNA viruses synthesize their own ncRNAs. Like their host counterparts, viral ncRNAs associate with proteins that are essential for their stability, function, or both. Diverse biological roles—including the...

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Detalles Bibliográficos
Autores principales: Tycowski, Kazimierz T., Guo, Yang Eric, Lee, Nara, Moss, Walter N., Vallery, Tenaya K., Xie, Mingyi, Steitz, Joan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378190/
https://www.ncbi.nlm.nih.gov/pubmed/25792595
http://dx.doi.org/10.1101/gad.259077.115
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author Tycowski, Kazimierz T.
Guo, Yang Eric
Lee, Nara
Moss, Walter N.
Vallery, Tenaya K.
Xie, Mingyi
Steitz, Joan A.
author_facet Tycowski, Kazimierz T.
Guo, Yang Eric
Lee, Nara
Moss, Walter N.
Vallery, Tenaya K.
Xie, Mingyi
Steitz, Joan A.
author_sort Tycowski, Kazimierz T.
collection PubMed
description Eukaryotic cells produce several classes of long and small noncoding RNA (ncRNA). Many DNA and RNA viruses synthesize their own ncRNAs. Like their host counterparts, viral ncRNAs associate with proteins that are essential for their stability, function, or both. Diverse biological roles—including the regulation of viral replication, viral persistence, host immune evasion, and cellular transformation—have been ascribed to viral ncRNAs. In this review, we focus on the multitude of functions played by ncRNAs produced by animal viruses. We also discuss their biogenesis and mechanisms of action.
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spelling pubmed-43781902015-09-15 Viral noncoding RNAs: more surprises Tycowski, Kazimierz T. Guo, Yang Eric Lee, Nara Moss, Walter N. Vallery, Tenaya K. Xie, Mingyi Steitz, Joan A. Genes Dev Review Eukaryotic cells produce several classes of long and small noncoding RNA (ncRNA). Many DNA and RNA viruses synthesize their own ncRNAs. Like their host counterparts, viral ncRNAs associate with proteins that are essential for their stability, function, or both. Diverse biological roles—including the regulation of viral replication, viral persistence, host immune evasion, and cellular transformation—have been ascribed to viral ncRNAs. In this review, we focus on the multitude of functions played by ncRNAs produced by animal viruses. We also discuss their biogenesis and mechanisms of action. Cold Spring Harbor Laboratory Press 2015-03-15 /pmc/articles/PMC4378190/ /pubmed/25792595 http://dx.doi.org/10.1101/gad.259077.115 Text en © 2015 Tycowski et al.; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Review
Tycowski, Kazimierz T.
Guo, Yang Eric
Lee, Nara
Moss, Walter N.
Vallery, Tenaya K.
Xie, Mingyi
Steitz, Joan A.
Viral noncoding RNAs: more surprises
title Viral noncoding RNAs: more surprises
title_full Viral noncoding RNAs: more surprises
title_fullStr Viral noncoding RNAs: more surprises
title_full_unstemmed Viral noncoding RNAs: more surprises
title_short Viral noncoding RNAs: more surprises
title_sort viral noncoding rnas: more surprises
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378190/
https://www.ncbi.nlm.nih.gov/pubmed/25792595
http://dx.doi.org/10.1101/gad.259077.115
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AT vallerytenayak viralnoncodingrnasmoresurprises
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AT steitzjoana viralnoncodingrnasmoresurprises

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