An evolutionarily conserved DNA architecture determines target specificity of the TWIST family bHLH transcription factors

Basic helix–loop–helix (bHLH) transcription factors recognize the canonical E-box (CANNTG) to regulate gene transcription; however, given the prevalence of E-boxes in a genome, it has been puzzling how individual bHLH proteins selectively recognize E-box sequences on their targets. TWIST is a bHLH t...

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Detalles Bibliográficos
Autores principales: Chang, Andrew T., Liu, Yuanjie, Ayyanathan, Kasirajan, Benner, Chris, Jiang, Yike, Prokop, Jeremy W., Paz, Helicia, Wang, Dong, Li, Hai-Ri, Fu, Xiang-Dong, Rauscher, Frank J., Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378193/
https://www.ncbi.nlm.nih.gov/pubmed/25762439
http://dx.doi.org/10.1101/gad.242842.114

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