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The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing
Piwi–piRNA (Piwi-interacting RNA) ribonucleoproteins (piRNPs) enforce retrotransposon silencing, a function critical for preserving the genome integrity of germ cells. The molecular functions of most of the factors that have been genetically implicated in primary piRNA biogenesis are still elusive....
Autores principales: | Vourekas, Anastassios, Zheng, Ke, Fu, Qi, Maragkakis, Manolis, Alexiou, Panagiotis, Ma, Jing, Pillai, Ramesh S., Mourelatos, Zissimos, Wang, P. Jeremy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378194/ https://www.ncbi.nlm.nih.gov/pubmed/25762440 http://dx.doi.org/10.1101/gad.254631.114 |
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