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Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation

Pancreatic ductal adenocarcinoma (PDA) develops predominantly through pancreatic intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasm (IPMN) precursor lesions. Pancreatic acinar cells are reprogrammed to a “ductal-like” state during PanIN-PDA formation. Here, we demonstrate...

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Detalles Bibliográficos
Autores principales:	Roy, Nilotpal, Malik, Shivani, Villanueva, Karina E., Urano, Atsushi, Lu, Xinyuan, Von Figura, Guido, Seeley, E. Scott, Dawson, David W., Collisson, Eric A., Hebrok, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378197/ https://www.ncbi.nlm.nih.gov/pubmed/25792600 http://dx.doi.org/10.1101/gad.256628.114

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