SCF(JFK) is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer

Loss of function/dysregulation of inhibitor of growth 4 (ING4) and hyperactivation of NF-κB are frequent events in many types of human malignancies. However, the molecular mechanisms underlying these remarkable aberrations are not understood. Here, we report that ING4 is physically associated with J...

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Detalles Bibliográficos
Autores principales: Yan, Ruorong, He, Lin, Li, Zhongwu, Han, Xiao, Liang, Jing, Si, Wenzhe, Chen, Zhe, Li, Lei, Xie, Guojia, Li, Wanjin, Wang, Peiyan, Lei, Liandi, Zhang, Hongquan, Pei, Fei, Cao, Dengfeng, Sun, Luyang, Shang, Yongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378198/
https://www.ncbi.nlm.nih.gov/pubmed/25792601
http://dx.doi.org/10.1101/gad.254292.114

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