Loss of neuronal GSK3β reduces dendritic spine stability and attenuates excitatory synaptic transmission via β-catenin

Central nervous glycogen synthase kinase 3β (GSK3β) is implicated in a number of neuropsychiatric diseases, such as bipolar disorder, depression, schizophrenia, fragile X syndrome or anxiety disorder. Many drugs employed to treat these conditions inhibit GSK3β either directly or indirectly. We studi...

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Detalles Bibliográficos
Autores principales: Ochs, S M, Dorostkar, M M, Aramuni, G, Schön, C, Filser, S, Pöschl, J, Kremer, A, Van Leuven, F, Ovsepian, S V, Herms, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378257/
https://www.ncbi.nlm.nih.gov/pubmed/24912492
http://dx.doi.org/10.1038/mp.2014.55

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