Ca(2+)/Calmodulin-dependent protein Kinase II interacts with group I Metabotropic Glutamate and facilitates Receptor Endocytosis and ERK1/2 signaling: role of β-Amyloid

BACKGROUND: Agonist stimulation of Group I metabotropic glutamate receptors (mGluRs) initiates their coupling to the heterotrimeric G protein, Gα(q/11), resulting in the activation of phospholipase C, the release of Ca(2+) from intracellular stores and the subsequent activation of protein kinase C....

Descripción completa

Detalles Bibliográficos
Autores principales: Raka, Fitore, Di Sebastiano, Andrea R, Kulhawy, Stephanie C, Ribeiro, Fabiola M, Godin, Christina M, Caetano, Fabiana A, Angers, Stephane, Ferguson, Stephen S G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378271/
https://www.ncbi.nlm.nih.gov/pubmed/25885040
http://dx.doi.org/10.1186/s13041-015-0111-4

Ejemplares similares

Ejemplares similares