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Chitosan/siRNA functionalized titanium surface via a layer-by-layer approach for in vitro sustained gene silencing and osteogenic promotion

Titanium surface modification is crucial to improving its bioactivity, mainly its bone binding ability in bone implant materials. In order to functionalize titanium with small interfering RNA (siRNA) for sustained gene silencing in nearby cells, the layer-by-layer (LbL) approach was applied using so...

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Detalles Bibliográficos
Autores principales: Song, Wen, Song, Xin, Yang, Chuanxu, Gao, Shan, Klausen, Lasse Hyldgaard, Zhang, Yumei, Dong, Mingdong, Kjems, Jørgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378287/
https://www.ncbi.nlm.nih.gov/pubmed/25848254
http://dx.doi.org/10.2147/IJN.S76513