Cargando…

Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators

Macrophages respond to the TLR4 agonist LPS with a sequential transcriptional cascade controlled by a complex regulatory network of signaling pathways and transcription factors. At least two distinct pathways are currently known to be engaged by TLR4 and are distinguished by their dependence on the...

Descripción completa

Detalles Bibliográficos
Autores principales: Raza, Sobia, Barnett, Mark W., Barnett-Itzhaki, Zohar, Amit, Ido, Hume, David A., Freeman, Tom C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Leukocyte Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378362/
https://www.ncbi.nlm.nih.gov/pubmed/24721704
http://dx.doi.org/10.1189/jlb.6HI0313-169R